|Molecular Formula||C10H17N6O12P3 (free acid)|
|Molecular Weight||506.20 (free acid)|
|Structure\Application||Phosphate modified Nucleotides|
|Purity||≥ 95% by HPLC|
|Related CAS||114635-43-7 (Tetrasodium salt)|
|Synonyms||(AMPNPP); Adenosine-5'-[(α,β)-imido]triphosphate, Sodium salt|
DMNPE-caged ATP is a nucleotide analogue of ATP which esterified with a blocking group. It blocks ATP-sensitive K channels in cardiac muscle.
ddATP-α-S is used in mass spectrometric genotyping.
ATPγS is an agonist of G protein-coupled P2Y2 and P2Y11 receptors (pEC50 = 5.52 for P2Y11). It has been used to identify kinase substrates, used as a reagent in...
6-PhEt-ATP-γ-S is an analogue used to specifically interact with modified receptor proteins (chemical genetics approach).
Sp-2'-O-Me-GTP-α-S is an analogue of GTP that can be used for enzymatic introduction of phosphorothioate and modified 2'-OH groups into RNA.
GTPαS can be accomplished by 50-thiophosphorylation of 7-methylguanosine in (MeO)3PO in the presence of 2,6-lutidine,12 followed by addition of tributylammonium...
ddTTP-α-S is used in mass spectrometric genotyping.
6-cHe-ATP-γ-S is an analogue used to specifically interact with modified receptor proteins (chemical genetics approach).