AP4A - CAS 5542-28-9
Catalog number: 5542-28-9
Category: Nucleotides
Molecular Formula:
C20H28N10O19P4 (free acid)
Molecular Weight:
836.39 (free acid)
COA:
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Structure\Application:
Dinucleoside Polyphosphates | Nucleotides applied on Proteins/Enzymes
Description:
AP4A is a signal molecule for DNA replication in mammalian cells. AP4A is used as a primer for oligoadenylate synthesis catalyzed by interferon-inducible 2-5A synthetase. AP4A is an inhibitor of eosinophil-derived neurotoxin (EDN).
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Brife Description:
signal molecule for DNA replication, inhibitor of eosinophil-derived neurotoxin (EDN)
Purity:
≥ 95% by HPLC
Appearance:
clear aqueous solution
Synonyms:
(AppppA); P1-(5'-Adenosyl) P4-(5'-adenosyl) tetraphosphate, Sodium salt
MSDS:
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Application:
AP4A is an inhibitor of eosinophil-derived neurotoxin (EDN).
InChIKey:
YOAHKNVSNCMZGQ-XPWFQUROSA-N
InChI:
InChI=1S/C20H28N10O19P4/c21-15-9-17(25-3-23-15)29(5-27-9)19-13(33)11(31)7(45-19)1-43-50(35,36)47-52(39,40)49-53(41,42)48-51(37,38)44-2-8-12(32)14(34)20(46-8)30-6-28-10-16(22)24-4-26-18(10)30/h3-8,11-14,19-20,31-34H,1-2H2,(H,35,36)(H,37,38)(H,39,40)(H,41,42)(H2,21,23,25)(H2,22,24,26)/t7-,8-,11-,12-,13-,14-,19-,20-/m1/s1
Canonical SMILES:
C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C5N=CN=C6N)O)O)O)O
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CAS 5542-28-9 AP4A

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