Anle138b - CAS 882697-00-9
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C16H11BrN2O2
Molecular Weight:
343.17
COA:
Inquire
Targets:
Others
Description:
Anle138b is a novel fluorescent oligomer modulator and an aggregation inhibitor. In vitro, anle138b blocked the formation of pathological aggregates of prion protein (PrPSc) and of α-synuclein.
Publictions citing BOC Sciences Products
  • >> More
Synonyms:
5-(1,3-benzodioxol-5-yl)-3-(3-bromophenyl)-1H-pyrazole; 3-(1,3-benzodioxol-5-yl)-5-(3-bromophenyl)-1H-pyrazole; anle138b
Solubility:
DMSO
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
527.3±50.0 ℃ at 760 Torr
Density:
1.567±0.06 g/cm3
InChIKey:
RCQIIBJSUWYYFU-UHFFFAOYSA-N
InChI:
1S/C16H11BrN2O2/c17-12-3-1-2-10(6-12)13-8-14(19-18-13)11-4-5-15-16(7-11)21-9-20-15/h1-8H,9H2,(H,18,19)
Canonical SMILES:
C1OC2=C(O1)C=C(C=C2)C3=CC(=NN3)C4=CC(=CC=C4)Br
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Products


Schisantherin E
(CAS: 64917-83-5)

Source from the seeds of Schisandra chinensis (Turcz.) Baill, shows good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffer...

CAS 2451-01-6 Terpin monohydrate

Terpin monohydrate
(CAS: 2451-01-6)

Terpin hydrate is a kind of plant extract, which exists in various plant essential oils such as laurel and rosemary oil. It could be used in the treatment of ac...

CP-60949-4
(CAS: 17518-97-7)

CP-60949-4, a quinazolin derivative, could be probably useful in sorts of biological studies.

AL-321
(CAS: 74772-68-2)

AL-321 is a bio-active chemical, but no detailed information has been published yet.

CAS 112111-44-1 (S)-(+)-Modafinic acid

(S)-(+)-Modafinic acid
(CAS: 112111-44-1)

(S)-(+)-Modafinic acid is the major metabolite of Modafinil(HY-10521A), which is a central nervous system vigilance promoting agent, which posseses neuroprotect...

CAS 127967-03-7 PD 131628

PD 131628
(CAS: 127967-03-7)

PD 131628 is a new fluoroquinolone as the bioactive form of PD 131112 which is a antibacterial agent originated by Pfizer. PD 131112 can be used for the treatme...

CAS 41708-72-9 ToCainide

ToCainide
(CAS: 41708-72-9)

Tocainide, a lidocaine analog, is a class Ib antiarrhythmic agent.

MK-0493
(CAS: 455957-71-8)

MK-0493 is a novel, potent, and selective agonist of MC4R( melanocortin receptor 4) , which is one of the best-validated genetic targets and considered one of t...

CAS 189950-66-1 Ac-DEVD-pNA

Ac-DEVD-pNA
(CAS: 189950-66-1)

Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) (Km=9.7μM) and related cysteine proteases.

Elamipretide
(CAS: 736992-21-5)

Elamipretide is a cardiolipin peroxidase inhibitor and mitochondria-targeting peptide under the development of Stealth BioTherapeutics. It can Improve left Vent...

CAS 79233-15-1 Deoxyandrographolide

Deoxyandrographolide
(CAS: 79233-15-1)

Deoxyandrographolide is a natural compound extracted from the herbs of Andrographis paniculata (Burm. f.) Nees. It could potently inhibit the growth of liver (H...

PD-116152
(CAS: 101708-64-9)

PD-116152 is a novel and highly substituted phenazine. It has antitumor activity. It was isolated from the culture broth of a Streptomyces sp.

CAS 4969-02-2 Metixene

Metixene
(CAS: 4969-02-2)

Metixene is an anticholinergic used as an antiparkinsonian agent for the symptomatic treatment of parkinsonism.

CAS 108321-42-2 Geneticin (G418 Sulfate)

Geneticin (G418 Sulfate)
(CAS: 108321-42-2)

Geneticin blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.G418 is an inhibitor of many pro- and eukaryot...

CAS 900510-03-4 PF-3274167

PF-3274167
(CAS: 900510-03-4)

PF-3274167, also known as PF-03274167 or PF-327,4167, is a potent and selective, high-affinity nonpeptide oxytocin receptor antagonist.

CAS 173528-92-2 HMN-154

HMN-154
(CAS: 173528-92-2)

HMN-154, a novel benzenesulfonamide anticancer drug, inhibits KB (IC50= 0.0026 μg/mL) and colon38 cells (IC50= 0.003 μg/mL).

CAS 59865-13-3 Cyclosporine

Cyclosporine
(CAS: 59865-13-3)

Immunosuppressant; inhibits phosphatase activity of calcineurin (IC50 = 5 nM). Also inhibits formation and opening of the mitochondrial permeability transition ...

CAS 1260075-17-9 PKR-IN-1

PKR-IN-1
(CAS: 1260075-17-9)

Activator of pyruvate kinase isoenzyme M2 (PKM2), an enzyme involved in glycolysis. Since all tumor cells exclusively express the embryonic M2 isoform of PK, it...

CAS 36062-07-4 Octahydrocurcumin

Octahydrocurcumin
(CAS: 36062-07-4)

OKT3-induced PBMC proliferation was inhibited by octahydrocurcumin with IC50 of 82 uM. The investigated substances with the strongest effect on radical scavengi...

CAS 697797-51-6 UAMC00039 dihydrochloride

UAMC00039 dihydrochloride
(CAS: 697797-51-6)

UAMC00039 dihydrochloride is a potent, reversible and competitive dipeptidyl peptidase II inhibitor (IC50= 0.48 nM) with selectivity against DPP-9, DPP-8 and DP...

Chemical Structure

CAS 882697-00-9 Anle138b

Quick Inquiry

Verification code

Featured Items