Anisotropine methyl bromide - CAS 80-50-2
Catalog number: 80-50-2
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
Molecular Weight:
Anisotropine methylbromide is a muscarinic antagonist and antispasmodic. It was an adjunct in the treatment of peptic ulcer and promoted as being more specific to the gastrointestinal tract than other anticholinergics. But now, anisotropine methylbromide has been superseded by more effective agents in the treatment of peptic ulcer disease.
(3-endo)-8,8-Dimethyl-3-[(1-oxo-2-propylpentyl)oxy]-8-azoniabicyclo[3.2.1]octane Bromide; 3α-Hydroxy-8-methyl-1αH,5αH-tropanium Bromide 2-Propylvalerate; endo-8,8-Dimethyl-3-[(1-oxo-2-propylpentyl)oxy]- 8-azoniabicyclo[3.2.1]octane Bromide; 8-Methyltropinium Bromide, 2-Propylvalerate; 8-Methyl-3-(2-propylpentanoyloxy)tropinium Bromide; 8-Methyltropinium Bromide 2-Propylpentanoate; Anisotropine Methobromide; Lytispasm; Octatropine Methylbromide; Valpin; Valpin 50; Vapin
Soluble in DMSO
-20℃ Freezer
peptic ulcer
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Canonical SMILES:
1.Effect of nighttime anisotropine methyl bromide of duodenal ulcer healing and pain: a double-blind controlled trial.
Bowers JH, Forbes JA, Freston JW. J Clin Pharmacol. 1978 Jul;18(7):365-71.
Anisotropine methyl bromide, an anticholinergic, 80 mg given orally at 8 P.M., suppresses gastric acid secretion through the night without significant side effects. Thirty patients with endoscopy-proved symptomatic duodenal ulcer disease completed a randomized, double-blind, placebo-controlled trial of nighttime anisotropine methyl bromide therapy. Eleven (69 per cent) of 16 anisotropine methyl bromide-treated and six (43 per cent) of 14 placebo-treated subjects healed their ulcers within two weeks of starting treatment. The anisotropine methyl bromide-treated subjects averaged 0.63 +/- 0.27 (mean +/- S.E.) episodes of nocturnal pain during the treatment period versus 2.71 +/- 1.08 episodes in the placebo group (P = 0.06). This is the first reported study of this type designed to evaluate the efficacy of an anticholinergic agent in the healing of duodenal ulcers. Although not conclusive, the results suggest nighttime anisotropine methyl bromide therapy may be useful in the treatment of duodenal ulcer disease.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related mAChR Products

CAS 26095-59-0 Otilonium Bromide

Otilonium Bromide
(CAS: 26095-59-0)

Otilonium Bromide is an antimuscarinic used as a spasmolytic agent.

CAS 132829-83-5 Espatropate

(CAS: 132829-83-5)

Espatropate is a Muscarinic receptor antagonist originated by Pfizer. It is a bronchodilator with antimuscarinic activity. No development was reported for the t...

CAS 596-51-0 Glycopyrrolate bromide

Glycopyrrolate bromide
(CAS: 596-51-0)

Glycopyrrolate bromide is a muscarinic competitive antagonist used as an antispasmodic.

CAS 133099-04-4 Darifenacin

(CAS: 133099-04-4)

Darifenacin hydrobromide is an antispasmodic muscarinic antagonist, selective for blocking the M3 muscarinic acetylcholine receptor, which is primarily responsi...

CAS 124937-52-6 Tolterodine tartrate

Tolterodine tartrate
(CAS: 124937-52-6)

Tolterodine has a high affinity and specificity for muscarinic receptors in vitro and it exhibits selectivity for the urinary bladder over salivary glands in vi...

CAS 142999-59-5 GYKI-46903 HCl

GYKI-46903 HCl
(CAS: 142999-59-5)

GYKI-46903 is a Muscarinic M3 receptor and Serotonin 3 receptor antagonist. In displacement studies, the pIC50 values of GYKI-46903 against [3H]granisetron bind...

CAS 2092923-21-0 VU 6008667

VU 6008667
(CAS: 2092923-21-0)

VU 6008667 is a selective negative allosteric modulator (NAM) of M5 muscarinic acetylcholine receptor (mAChR) (IC50 values of 1.2 and 1.6 μM in human and rat M5...

CAS 77-19-0 Dicycloverine (Dicyclomine)

Dicycloverine (Dicyclomine)
(CAS: 77-19-0)

Dicycloverine, also known as dicyclomine, is an anticholinergic that blocks muscarinic receptors.

Chemical Structure

CAS 80-50-2 Anisotropine methyl bromide

Quick Inquiry

Verification code

Featured Items