Amodiaquin dihydrochloride dihydrate - CAS 6398-98-7
Catalog number: 6398-98-7
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C20H24Cl3N3O
Molecular Weight:
428.78
COA:
Inquire
Targets:
HMTase
Description:
Amodiaquine, a 4-aminoquinoquinoline compound, has is a histamine N-methyltransferase inhibitor, used as an antimalarial and anti-inflammatory agent been used as both an antimalarial and an anti-inflammatory agent for more than 40 years.
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Purity:
≥98%
Appearance:
Light yellow to yellow Solid
Synonyms:
Amodiaquine HCl; 4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol;dihydrate;dihydrochloride;
Solubility:
Soluble in DMSO
Storage:
Store at -20 °C
MSDS:
Inquire
Application:
An antimalarial.
Quality Standard:
Enterprise Standard/USP
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Grams-Kilos
Melting Point:
>197°C (dec.)
InChIKey:
YVNAYSHNIILOJS-UHFFFAOYSA-N
InChI:
1S/C20H22ClN3O.2ClH.2H2O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19;;;;/h5-12,25H,3-4,13H2,1-2H3,(H,22,23);2*1H;2*1H2
Canonical SMILES:
CCN(CC)CC1=C(C=CC(=C1)NC2=C3C=CC(=CC3=NC=C2)Cl)O.O.O.Cl.Cl
Current Developer:
Drugs for Neglected Diseases Initiative Foundation; sanofi-aventis
1.The antifertility effect of amodiaquine hydrochloride.
Gbotolorun SC1, Osinubi AA, Oremosu AA, Noronha CC. Nig Q J Hosp Med. 2011 Oct-Dec;21(4):271-5.
BACKGROUND: A number of antimalarial compounds and herbs have been reported to possess antifertility actions. Amodiaquine (AQ) belongs to the same class of drugs as chloroquine. Chloroquine has been reported to disrupt the oestrus cycle, block ovulation and consequently reduce fertility.
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CAS 6398-98-7 Amodiaquin dihydrochloride dihydrate

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