|Description||Amitriptyline inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM, respectively.|
Hydrastine, a natural alkaloid compound, could be used as a dopamine biosynthesis inhibitor.
Pamidronic acid (INN) or pamidronate disodium (USAN), pamidronate disodium pentahydrate is a nitrogen-containingbisphosphonate, used to prevent osteoporosis.
Atractylenolide II is a sesquiterpene compound isolated from the dried rhizome of Atractylodes macrocephala, which has anti-proliferative activity.
Ginsenoside Rf, extracted from the traditional Chinese herb ginseng used as an aldose reductase inhibitor and my exert anti-inflammatory and immunomodulatory ac...
Camostat (INN) or FOY-305 is a serine protease inhibitor. Serine protease enzymes have a variety of functions in the body, and so camostat has a diverse range o...
Sulfabenzamide is a widely used intermediate in many chemical areas and has been found to have antibacterial activity.
When tested against a number of release-inducing stimuli, this active molecular can inhibit evoked [3H]GABA release.
Hemoglobin Modulators-1, a substituted benzaldehyde compound that can modulate sickle hemoglobin (HbS) for treatment of disorders.
Glycitin is an isoflavonoid recently found in flowers of Pueraria thunbergianal. It can be modified into the metabolite glycitein which has anti-inflammatory pr...
Astragalin is a flavonoid with anti-inflammatory activity and newly found in persimmon leaves and green tea seeds.
Nedocromil is an inhaled anti-inflammatory agent for the preventive management of asthma.
Exemestane is an aromatase inhibitor, inhibits human placental and rat ovarian aromatase with IC50 of 30 nM and 40 nM, respectively.
SPDB, a pyridyldithioyl compound, has been found to link to DM4 conjugates and probably influence the releasement of cytotoxic metabolitesin.
This molecular has a favorable potency versus human β-amyloid plaque and has been radiolabeled for further evaluation in in vitro binding and in vivo PET imagin...
Creatinine is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body.
Mivacurium is a bisbenzylisoquinolinium based and a short-duration non-depolarizing neuromuscular-blocking drug or skeletal muscle relaxant. It binds competitiv...
D-Pantothenic acid, also called vitamin B5, is a water-soluble vitamin and an essential nutrient for many animals.
Lipid peroxidation inhibitor 1
A lipid peroxidation inhibitor (IC50= 0.07 μM).
Cucurbitacin B, an oxygenated tetracyclic triterpenoid compound extracted from Cucurbitaceae plant species, is a long-term anticancer agent by disruption of mic...
2-Hydroxy-4-methoxybenzophenone (benzophenone-3) is commonly employed as broad-band UV-filter in sunscreen cosmetic products. It protects skin from the deleteri...