Amitraz - CAS 33089-61-1
Catalog number: 33089-61-1
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
Molecular Weight:
Amitraz is a non-systemic acaricide and insecticide, as an antiparasitic used to control red spider mites, leaf miners and scale insects.
Beige to Pale Yellow Solid
N’-(2,4-Dimethylphenyl)-N-[[(2,4-dimethylphenyl)imino]methyl]-N-methyl-methanimidamide; 2-methyl-1,3-di(2,4-xylylimino)-2-azapropane
Soluble in DMSO
Store at R. T.
an antiparasitic used to control red spider mites, leaf miners and scale insects.
Quality Standard:
Enterprise Standard
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Melting Point:
86-87 °C
0.98 g/cm3
Canonical SMILES:
1.Straelensiosis in two cats and ten dogs from Israel.
Kaufmann R1, Bourdeau P2, Waldman L3, Amiel S4, Zur G1. J Small Anim Pract. 2015 Dec;56(12):723-7. doi: 10.1111/jsap.12374. Epub 2015 Jun 5.
Straelensiosis is uncommonly described outside Europe. This report describes straelensiosis in two cats and in ten dogs diagnosed with the disease outside Europe. Both cats displayed erythematous macules or nodules on the abdominal skin. One cat was extremely pruritic, while in the other the lesions were incidental findings when the cat was presented for neutering. The mites were noted in skin scrapings in both cats and histopathologically in one cat. All dogs showed a general distribution of papules, and intense pruritus was noted in six dogs. The diagnosis in all dogs was based on histopathology. Treatment of the animals in this study varied, and among the various administrated treatments, amitraz showed promising results.
2.Comparison of tau-fluvalinate, acrinathrin, and amitraz effects on susceptible and resistant populations of Varroa destructor in a vial test.
Kamler M1,2, Nesvorna M3, Stara J3, Erban T3, Hubert J4. Exp Appl Acarol. 2016 May;69(1):1-9. doi: 10.1007/s10493-016-0023-8. Epub 2016 Feb 24.
The parasitic mite Varroa destructor is a major pest of the western honeybee, Apis mellifera. The development of acaricide resistance in Varroa populations is a global issue. Discriminating concentrations of acaricides are widely used to detect pest resistance. Two methods, using either glass vials or paraffin capsules, are used to screen for Varroa resistance to various acaricides. We found the glass vial method to be useless for testing Varroa resistance to acaridices, so we developed a polypropylene vial bioassay. This method was tested on tau-fluvalinate-, acrinathrin-, and amitraz-resistant mite populations from three apiaries in Czechia. Acetone was used as a control and technical grade acaricide compounds diluted in acetone were applied to the polypropylene vials. The solutions were spread on the vial surface by rolling the vial, and were then evaporated. Freshly collected Varroa females were placed in the vials and the mortality of the exposed mites was measured after 24 h.
3.The role of octopamine receptor agonists in the synergistic toxicity of certain insect growth regulators (IGRs) in controlling Dengue vector Aedes aegypti (Diptera: Culicidae) mosquito.
Ahmed MA1, Vogel CF2. Acta Trop. 2016 Mar;155:1-5. doi: 10.1016/j.actatropica.2015.11.015. Epub 2015 Dec 7.
The synergistic action of octopamine receptor agonists (OR agonists) on many insecticide classes (e.g., organophosphorus, pyrethroids, and neonicotinoids) on Aedes aegypti L. has been reported recently. An investigation of OR agonist's effect on insect growth regulators (IGRs) was undertaken to provide a better understanding of the mechanism of action. Based on the IGR bioassay, pyriproxyfen was the most potent IGR insecticide tested (EC50=0.0019ng/ml). However, the lethal toxicity results indicate that diafenthiuron was the most potent insecticide (LC50=56ng/cm(2)) on A. aegypti adults after 24h of exposure. The same trend was true after 48 and 72h of exposure. Further, the synergistic effects of OR agonists plus amitraz (AMZ) or chlordimeform (CDM) was significant on adults. Among the tested synergists, AMZ increased the potency of the selected IGRs on adults the greatest. As results, OR agonists were largely synergistic with the selected IGRs.
4.Demodicosis caused by Demodex canis and Demodex cornei in dogs.
Sivajothi S1, Sudhakara Reddy B2, Rayulu VC1. J Parasit Dis. 2015 Dec;39(4):673-6. doi: 10.1007/s12639-013-0405-3. Epub 2013 Nov 26.
Two mongrel dogs aged between 7 and 9 months in a same house were presented to the clinics with a history of chronic dermatitis associated with pruritus. Clinical examination revealed presence of primary and secondary skin lesions on the face, around the ears, chin, neck, fore limbs and lateral abdomen. Examination of skin scrapings revealed Demodex cornei (majority) and D. canis (minority) in both the dogs. By using hair pluck examination D. canis were detected and by tape impression smears examination large number of adult short-tail Demodex mites were found. D. cornei was identified by based on the morphological characters including short opisthosoma with blind and round terminal end. Mean length of total body, opisthosoma of both types of the mites were differed statistically significant (P < 0.01) but gnathosoma and podosoma did not differ significantly (P > 0.05). Dogs were treated with daily oral ivermectin @ 500 μg/kg/day, external application of amitraz along with supportive therapy.
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CAS 33089-61-1 Amitraz

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