|Description||Amisulpride hydrochloride could inhibit radioligand binding to native dopamine D2 receptor in membranes from the rat striatum with an IC50 value of 21nM. It has been revealed to displace [3H]raclopride binding in vivo with an ED50 value of 17.3±1.86mg/kg in the rat limbic system. It has been noted to inhibit quinpirole-induced [3H]thymidine with an IC50 value of 22±3nM. It is used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder. It has been approved in February 2002 by FDA.|
|Synonyms||DAN 2163 hydrochloride;4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide;hydrochloride|
|Solubility||DMSO 74 mg/mL ; Water <1 mg/mL ; Ethanol 74 mg/mL|
|Application||Amisulpride hydrochloride is used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder.|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Current Developer||Amisulpride hydrochloride It has been approved in February 2002 by FDA.|
Sonepiprazole is a selective, brain penetrating and orally bioactive antagonist for the rat and human dopamine D4 receptor (Ki = 10 nM) with low affinity at oth...
Odapipam is a potent dopamine D1 antagonist.
Eticlopride is a selective dopamine D2 antagonist . It was initially developed as a potential antipsychotic agent. Now Eticlopride is primarily used in pharmaco...
MLS 1547 is a dopamine D2 receptor agonist. It may be used in the combination with antipsychotic drugs.
Tiapride is a D2 and D3 dopamine receptor antagonist used to treat a variety of neurological and psychiatric disorders.
Tetrahydroberberine is a protoberberine alkaloid acts as a calcium channel blocker.
A modulator of dopamine receptor
UNC 9994 hydrochloride is a β-arrestin-biased functionally selective dopamine D2 receptor (D2R) agonist (Ki value 30 nM; EC50 value 50 nM in β-arrestin-2 recrui...