Amisulpride - CAS 71675-85-9
Catalog number: 71675-85-9
Category: Inhibitor
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Molecular Formula:
C17H27N3O4S
Molecular Weight:
369.48
COA:
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Targets:
Dopamine Receptor
Description:
Amisulpride is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder.
Purity:
>98%
MSDS:
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InChIKey:
NTJOBXMMWNYJFB-UHFFFAOYSA-N
InChI:
InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21)
Canonical SMILES:
CCN1CCCC1CNC(=O)C2=CC(=C(C=C2OC)N)S(=O)(=O)CC
1.A liquid chromatography-tandem mass spectrometry method for quantifying amisulpride in human plasma and breast milk, applied to measuring drug transfer to a fully breast-fed neonate.
O'Halloran SJ1, Wong A, Joyce DA. Ther Drug Monit. 2016 Mar 17. [Epub ahead of print]
BACKGROUND: Amisulpride is a second generation atypical antipsychotic drug. The management of psychosis exacerbation in late pregnancy or during lactation is often hampered by inadequate knowledge of risk to the baby from placental transfer or breast milk transfer of drugs. There is no specific information on adverse effects from amisulpride. In order to gather guiding information from one mother - baby pair, we conducted a drug concentration study on the 4 post-natal day and developed a novel liquid chromatography-tandem mass spectrometry method with application to the very small plasma volumes obtainable from a neonate, requiring 15 μL of plasma, and with application to human breast milk.
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CAS 71675-85-9 Amisulpride

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