|Description||Aminopotentidine is a high selectivity and high affinity histamine H2 receptor antagonist. Its KB values are 220 and 280 nM at human and guinea pig H2 receptors respectively. It is the precursor for the synthesis of the [125I]-iodo derivative, so it can be used in the synthetic preparation of an iodo derivative.|
|Purity||≥97% by HPLC|
KP136, an antiallergic agent, remarkably inhibited the passive cutaneous anaphylaxis (PCA) with intravenous and oral dosing. KP-136 is an oral potent inhibitor ...
Chlorphenoxamine is an analog of diphenhydramine. It has antimuscarinic and antihistaminic properties. It has been used as an antipruritic and antiparkinsonian ...
Ebrotidine(FI 3542), a competitive H2-receptor antagonist, has gastroprotective activity under the condition of gastric mucosal damage caused by some stress res...
Brompheniramine hydrogen maleate
Brompheniramine hydrogen maleate is a histamine H1 receptors antagonist.
Olopatadine HCl is a histamine blocker and mast cell stabilizer with an IC50 of 559 μM for the release of histamine
Clobenpropit dihydrobromide is a highly potent histamine H3 antagonist/inverse agonist (pA2=9.93) that can cross blood-brain barrier. It also displays partial a...
Proxyfan oxalate is a high affinity histamine H3 receptor ligand (pKi = 8.62), acting as a protean agonist with activity ranges from full agonist to inverse ago...
Dimethindene is a histamine H1 antagonist of high potency used orally and locally as an antipruritic.