|Description||Aminophylline is a competitive nonselective phosphodiesterase inhibitor with an IC50 of 0.12 mM and also a nonselective adenosine receptor antagonist.|
EHNA hydrochloride is a selective inhibitor of cGMP-stimulated phosphodiesterase (PDE2) (IC50 = 0.8 - 4 μM) and also an inhibitor of adenosine deaminase. EHNA i...
Udenafil is an oral PDE5 inhibitor. Udenafil significantly increased cAMP and cGMP levels and were more highly distributed in the prostate than plasma. The T/P ...
Luteolin is a flavonoid found in Terminalia chebula with antioxidant and scavenging activity. It is a non-selective phisphodiesterase PDE inhibitor, and also in...
ML-030, a triazolothiadiazine, is a potent PDE4 inhibitor in a cell-based cyclic nucleotide-gated cation channel biosensor assay (EC50 = 18.7 nM), with IC50 of ...
BRL 50481 is a potent, selective substrate-competitive inhibitor of phosphodiesterase (PDE) 7 (Ki = 180 nM).
Paraxanthine is a metabolite of caffeine, and also acts as an inhibitor of phosphodiesterase 9 (PDE9) and an antagonist of adenosine receptors A1 and A2 (Kis = ...
A phosphodiesterase (PDE5) inhibitor, used to treat erectile dysfunction.
T 0156 hydrochloride
T 0156 hydrochloride is a potent and selective inhibitor of phosphodiesterase type 5 (PDE5). T 0156 exhibits higher selectivity than sildenafil (IC50 = 0.23, 56...