Aminophylline - CAS 317-34-0
Catalog number: 317-34-0
Category: Inhibitor
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Molecular Formula:
Molecular Weight:
Phosphodiesterase (PDE)
Aminophylline is a competitive nonselective phosphodiesterase inhibitor with an IC50 of 0.12 mM and also a nonselective adenosine receptor antagonist.
Canonical SMILES:
1.[An unusual case of acute aminophylline intoxication].
Manes M, Pellu V, Radin E, Molino A, Gabrielli D, Caputo D, Paternoster G, Torti P, Visetti E, Nebiolo PE. G Ital Nefrol. 2015 Nov-Dec;32(6). pii: gin/32.6.7.
Theophylline/aminophylline use for asthma and chronic obstructive pulmonary disease has declined over time, as new and safer therapies developed. However, theophylline/aminophylline overdose can occur. Hereby it is described an unusual case of severe aminophylline intoxication due to mesodermic injections treated with CVVHDF session.
2.Aminophylline and caffeine for reversal of adverse symptoms associated with regadenoson SPECT MPI.
Doran JA1, Sajjad W1, Schneider MD1, Gupta R1, Mackin ML1, Schwartz RG2,3. J Nucl Cardiol. 2016 Mar 29. [Epub ahead of print]
BACKGROUND: Aminophylline shortages led us to compare intravenous (IV) aminophylline with IV and oral (PO) caffeine during routine pharmacologic stress testing with SPECT MPI.
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CAS 317-34-0 Aminophylline

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