|Description||Amiloride HCl is a relatively selective inhibitor of the epithelial sodium channel (ENaC), used in the management of hypertension and congestive heart failure.|
Propoxycaine hydrochloride is the hydrochloride salt form of Propoxycaine used to control the pain of intramuscular injection of penicillin as well as in dentis...
Ranolazine is a calcium uptake inhibitor via the sodium/calcium channal, used to treat chronic angina.
Riluzole is a drug used to treat amyotrophic lateral sclerosis.
Encainide Hydrochloride is a sodium channel blocker and class Ic antiarrhythmic agent. It is a non-chiral and benzanilide derivative. It blocks voltage-gated so...
Lidocaine hydrochloride monohydrate
Lidocaine hydrochloride monohydrate is the hydrochloride monohydrate form of lidocaine, which is an aminoethylamide and a prototypical member of the amide class...
Co 102862, also known as V102862, an orally active anticonvulsant with robust activity, is a potent, broad-spectrum state-dependent inhibitor of mammalian volta...
Lamotrigine is an anticonvulsant, inhibiting glutamate release, possibly through inhibition of Na+, K+ and Ca2+ currents.
Phenytoin Sodium is a potent multi-channel blocker, which blocks Na+, K+ and Ca 2+ channels and selectively blocks persistent INaP over shorter INaP actions.
Nav1.7 inhibitor is a Voltage-gated sodium channel inhibitor that have probable effect in pain therapy and local anaesthesia.
This active molecular is a human Nav1.7 voltage gated sodium channel inhibitor with the IC50 value of 28 nM. PF-04856264 inhibits the Nav channel by interacting...
Nav1.7-IN-2, a voltage-gated sodium channels, could be probably effective in chronic pain therapy. IC50: 80 nM.
Mexiletine HCl belongs to Class IB anti-arrhythmic group of medicines, inhibits sodium channels to reduce the inward sodium current.
CGP-47292, a triazole compound, has been found to be a metabolite of CGP-33101 that could be used agaist Lennox-Gastaut syndrome as a Sodium Channel antagonist.
Funapide is a Nav1.7 and Nav1.8 voltage-gated sodium channel inhibitor under the development by Xenon Pharmaceuticals and Teva Pharmaceutical Industries. It is ...
PH-064 is a sodium channel inhibitor. It is extracted from patent FR 2879460 A1.
Sodium Channel inhibitor 1
Sodium Channel inhibitor 1, a 3-Oxoisoindoline-1-carboxamide derivative, is an effective voltage-gated sodium channel blocker that could be used for pain treatm...
Evenamide is a selective voltage-gated sodium and/or calcium channel modulator, including subtypes Nav1.3, Nav1.7, and Nav1.8. It may be potentia useful in pre...
This active molecular is a calcium channel antagonist with sodium channel stimulating property as a dihydropyridine. PD 122860 can increase left ventricular con...
Phenytoin is believed to protect against seizures by causing voltage-dependent block of voltage gated sodium channels.
Ropivacaine hydrochloride is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.