1.Colistin-sparing regimens against Klebsiella pneumoniae carbapenemase-producing K. pneumoniae isolates: Combination of tigecycline or doxycycline and gentamicin or amikacin.
Tang HJ1, Lai CC2, Chen CC3, Zhang CC4, Weng TC4, Chiu YH5, Toh HS4, Chiang SR4, Yu WL6, Ko WC7, Chuang YC8. J Microbiol Immunol Infect. 2016 Mar 31. pii: S1684-1182(16)30024-X. doi: 10.1016/j.jmii.2016.03.003. [Epub ahead of print]
BACKGROUND/PURPOSE: In vitro studies of the combination of an aminoglycoside with tigecycline or doxycycline against Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae isolates are rarely published. The goal of this study was to evaluate the antibacterial activity of the combination regimens.