|Description||AMI-193 has been found to be a selective 5-HT antagonist and could be also used as a starting reagent in some pharmaceutical synthesis.|
|Purity||≥99% by HPLC|
NAD 299 hydrochloride
NAD 299 hydrochloride is a 5-HT1A receptor antagonist. It can be used in psychotropic drug development.
Nelotanser is Serotonin 2A receptor inverse agonist. In Aug 2016, Axovant Sciences initiated a phase-II clinical trial in Lewy body disease in USA.
Pimavanserin is a potent and selective 5-HT2A receptor inverse agonist used in the treatment of Parkinson’s disease psychosis.
MDL 72832 hydrochloride
MDL 72832 hydrochloride is a potent ligand at 5-HT1A receptors, with mixed agonist and antagonist properties.
Vortioxetine is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, r...
3-AQC has been found to be a competitive 5-HT3 antagonist with widely differing activity in various tissues.
Elzasonan citrate is a selective 5-hydroxytryptamine 1B receptor antagonist for treat patients with major depressive disorder and obsessive compulsive disorder.
Harmine induces apoptosis and inhibits proliferation, migration and invasion of human gastric cancer cells, which may be mediated by down-regulation of COX-2 ex...