|Description||AMG-9810 is potent, non-vanilloid and selective TRPV1 receptor antagonist with IC50 value of 17 nM. It inhibits capsaicin-, proton-, heat- and endogenous ligand-induced activation of human and rat recombinant TRPV1 receptors. It displays antihyperalgesic properties in a rat model of inflammatory pain. It was developed by Amgen.|
|Appearance||White to beige powder|
|Synonyms||(2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl)phenyl]-2-propanamide;2-PropenaMide, N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-diMethylethyl)phenyl]-, (2E)-;(E)-3-(4-tert-butylphenyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)prop-2-enami|
|Solubility||DMSO: >5 mg/mL|
|Application||AMG-9810 displays antihyperalgesic properties.|
|Quality Standard||In-house standard|
|Quantity||Grams to Kilograms|
|Boiling Point||512.5±50.0 °C | Condition: Press: 760 Torr|
|Density||1.175±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr|
|Current Developer||AMG-9810 was developed by Amgen.|
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