AMG 837 calcium hydrate - CAS 1259389-38-2
Catalog number: 1259389-38-2
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C52H42CaF6O7
Molecular Weight:
455.45
COA:
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Targets:
GPR40
Description:
AMG 837 calcium hydrate is a potent GPR40 agonist(EC50=13 nM) with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents.
Purity:
0.98
Synonyms:
AMG-837; AMG837; AMG 837
MSDS:
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InChIKey:
CKOUAGZCYCFTKW-YDULTXHLSA-L
InChI:
InChI=1S/C26H21F3O3.Ca.2H2O/c1-2-4-21(16-25(30)31)20-9-13-24(14-10-20)32-17-18-5-3-6-22(15-18)19-7-11-23(12-8-19)26(27,28)29;;;/h3,5-15,21H,16-17H2,1H3,(H,30,31);;2*1H2/q;+2;;/p-2/t21-;;;/m0.../s1
Canonical SMILES:
CC#CC(CC(=O)O)C1=CC=C(C=C1)OCC2=CC=CC(=C2)C3=CC=C(C=C3)C(F)(F)F.[OH-].[OH-].[Ca+2]
Current Developer:
Amgen Inc
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