AMG-126737 - CAS 224054-76-6
Catalog number:
224054-76-6
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C33H38N6O6S2
Molecular Weight:
678.82
COA:
Inquire
Targets:
Others
Description:
AMG-126737 is a potent inhibitor of human lung mast cell tryptase (Ki = 90 nM), with greater than 10- to 200-fold selectivity versus other serine proteases.
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Purity:
>98%
Appearance:
White Solid
Synonyms:
3-[[4-[5-[4-[[(3-carbamimidoylphenyl)sulfonylamino]methyl]phenoxy]pentoxy]phenyl]methylsulfamoyl]benzenecarboximidamide; 1,5-bis-(4-((3-carbamimidoyl-benzenesulfonylamino)-methyl)-phenoxy)-pentane; AMG 126737; AMG-126737
MSDS:
Inquire
Melting Point:
207-209˚C
InChIKey:
CTLMBCYIAXNYOG-UHFFFAOYSA-N
InChI:
1S/C33H38N6O6S2/c34-32(35)26-6-4-8-30(20-26)46(40,41)38-22-24-10-14-28(15-11-24)44-18-2-1-3-19-45-29-16-12-25(13-17-29)23-39-47(42,43)31-9-5-7-27(21-31)33(36)37/h4-17,20-21,38-39H,1-3,18-19,22-23H2,(H3,34,35)(H3,36,37)
Canonical SMILES:
C1=CC(=CC(=C1)S(=O)(=O)NCC2=CC=C(C=C2)OCCCCCOC3=CC=C(C=C3)CNS(=O)(=O)C4=CC=CC(=C4)C(=N)N)C(=N)N
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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