AMD3465 hexahydrobromide - CAS 185991-07-5
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C24H38N6.6HBr
Molecular Weight:
896.07
COA:
Inquire
Targets:
CXCR | HIV
Description:
AMD3465 is a potent and highly selective monomacrocyclic CXCR4 antagonist (IC50= 0.75 nM). It potently inhibits HIV cell entry in vitro and causes leukocytosis and mobilizes haematopoietic stem cells in vivo. It dose dependently inhibits eosinophil recruitment during type-2 granuloma formation and interferes with primary and secondary T-cell activation events in lymphoid tissue.
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Brife Description:
A potent and highly selective monomacrocyclic CXCR4 antagonist (IC50= 0.75 nM)
Purity:
99.43 %
Related CAS:
185991-24-6 (free base)
Appearance:
Pale Yellow Solid
Solubility:
Soluble to 50 mM in water and to 25 mM in DMSO
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
InChIKey:
KREFHIHKCDVXCJ-UHFFFAOYSA-N
InChI:
1S/C24H38N6/c1-2-12-29-24(8-1)20-28-19-22-6-3-7-23(18-22)21-30-16-5-11-26-14-13-25-9-4-10-27-15-17-30/h1-3,6-8,12,18,25-28H,4-5,9-11,13-17,19-21H2
Canonical SMILES:
C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CNCC3=CC=CC=N3.Br.Br.Br.Br.Br.Br
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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CAS 185991-07-5 AMD3465 hexahydrobromide

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