|Description||AM580 is a stable retinobenzoic derivative originally synthesized as a RARα agonist (EC50 values are 0.3, 8.6 and 13 nM for RARα, RARβ and RARγ respectively).|
RX-195183 is an RARα agonist (Kd=3 nM) with potential antineoplastic activity, modulating the transcription of genes responsible for cell differentiation and pr...
Tazarotene could propel either early or late portions of the period leading to differentiation and G0 arrest and is interchangeable with an RARalpha-selective l...
HX-603 is a RXR agonist.
CD 2314 is a potent and selective RARβ receptor agonist (Kd = 145 and >3760 nM for RARβ and RARα receptors, respectively).
Palovarotene is a selective retinoic acid receptor gamma(RAR-γ) agonist for the treatment of emphysema. In small animal studies, palovarotene was claimed to rev...
CD1530 is a potent and selective retinoic acid receptor(RAR) agonist with Ki values of 150, 1500 and 2750 nM for RARγ, RARβ and RARα receptors respectively. It ...
LG 100754 is a RXR:PPARγ agonist. It can decrease glucose levels and relieve insulin resistance in mice. LG 100754 shows antidiabetic properties in vivo.
AC 55649 is a potent and isoform-selective RARβ2 receptor agonist (pEC50 = 6.9, 5.7 and 5.6 at RARβ2, RARβ1 and RARα, respectively). It causes inhibition of pro...