AM-8508 - CAS 1338483-67-2
Catalog number:
1338483-67-2
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C19H15FN8
Molecular Weight:
374.14
COA:
Inquire
Targets:
PI3K
Description:
AM-8508 is a selective Phosphatidylinositol-3-kinase delta (PI3Kδ) inhibitor. AM-8508 exhibits good cellular potency (in vitro pAKT IC50 = 4.6 nM ) and excellent HWB potency (HWB (pAKT) IC50 = 2.7 nM). AM-8508 inhibits KLH-specific antibodies in animal models and it may become a drug candidate for the treatment of human inflammatory diseases.
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Purity:
98%
Appearance:
Powder
Synonyms:
(S)-4-amino-6-((1-(6-fluoro-1-(pyridin-3-yl)-1H-benzo[d]imidazol-2-yl)ethyl)amino)pyrimidine-5-carbonitrile
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
inflammatory diseases
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
Canonical SMILES:
N#CC1=C(N[C@H](C2=NC3=CC=C(F)C=C3N2C4=CC=CN=C4)C)N=CN=C1N
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