AM-2099 - CAS 1443373-17-8
Category: Inhibitor
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Molecular Formula:
C19H13F3N4O3S2
Molecular Weight:
466.46
COA:
Inquire
Targets:
Sodium Channel
Description:
AM-2099 is a potent and selective inhibitor of voltage-gated sodium channel Nav1.7 (IC50= 0.16 μM) with excellent selectivity against hNav1.5 (IC50 > 30 uM).
Brife Description:
A potent and selective NaV1.7 Inhibitor
Synonyms:
4-[2-methoxy-4-(trifluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)quinazoline-7-sulfonamide; AM2099
Solubility:
DMSO: ≥150 mg/mL
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
572.1±60.0 ℃ at 760 Torr
Density:
1.531±0.06 g/cm3
InChIKey:
VSUDRCZPHWUXEW-UHFFFAOYSA-N
InChI:
1S/C19H13F3N4O3S2/c1-29-16-8-11(19(20,21)22)2-4-14(16)17-13-5-3-12(9-15(13)24-10-25-17)31(27,28)26-18-23-6-7-30-18/h2-10H,1H3,(H,23,26)
Canonical SMILES:
COC1=C(C=CC(=C1)C(F)(F)F)C2=NC=NC3=C2C=CC(=C3)S(=O)(=O)NC4=NC=CS4
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Chemical Structure

CAS 1443373-17-8 AM-2099

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