AM-156 - CAS 1224977-85-8
Catalog number: 1224977-85-8
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C23H23F3NNaO4
Molecular Weight:
457.42
COA:
Inquire
Targets:
Others
Description:
Prostanoid GD(2) is released from mast cells in response to allergen challenge. AM156 is a selective prostanoid DP(2) receptor antagonist and it inhibits sneezing and nasal rubs in a model of allergic rhinitis. It can also inhibits pulmonary inflammation and mucus hypersecretion induced by chronic inhalation of house dust mite. AM156 may be have beneficial effects for treatment of allergic rhinitis and asthma in the future.
Purity:
98%
Appearance:
Powder
Synonyms:
UNII-5V9HJQ1Y75;sodium 2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-methoxy-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-yl)acetate;1175525-98-0 (AM-156 free acid)
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
allergic rhinitis and asthma.
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
WFUYBZRTYBYLFG-UHFFFAOYSA-M
InChI:
1S/C23H24F3NO4.Na/c1-3-27(22(30)15-5-6-15)13-16-12-17(23(24,25)26)7-8-18(16)19-10-14(11-21(28)29)4-9-20(19)31-2;/h4,7-10,12,15H,3,5-6,11,13H2,1-2H3,(H,28,29);/q;+1/p-1 Download
Canonical SMILES:
CCN(Cc1cc(ccc1c2cc(ccc2OC)CC(=O)[O-])C(F)(F)F)C(=O)C3CC3.[Na+]
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Products


CAS 191089-60-8 K-7174 dihydrochloride

K-7174 dihydrochloride
(CAS: 191089-60-8)

K-7174, one of proteasome inhibitory homopiperazine derivatives, exhibits a therapeutic effect, which is stronger when administered orally than intravenously, w...

CAS 96020-91-6 Eflornithine hydrochloride, hydrate

Eflornithine hydrochloride, hydrate
(CAS: 96020-91-6)

Eflornithine hydrochloride, hydrate is a drug found to be effective in the treatment of facial hirsutism. It is a "suicide inhibitor," irreversibly binding to O...

CAS 52-21-1 Prednisolone Acetate

Prednisolone Acetate
(CAS: 52-21-1)

Prednisolone Acetate is a synthetic corticosteroid drug that is particularly effective as an immunosuppressant agent.

CAS 1322598-09-3 CATPB

CATPB
(CAS: 1322598-09-3)

CATPB is a human FFA2 inverse agonist (pKi = 7.87). It increases forskolin-induced cAMP production, and inhibits acetate-induced MAPK signaling in cells express...

GSK-484
(CAS: 1652591-81-5)

GSK-484, a benzoimidazole derivative, has been found to be an effective reversible PAD-4 inhibitor that could be significant in some inflammation and immune res...

CAS 877052-79-4 GPBAR-A

GPBAR-A
(CAS: 877052-79-4)

GPBAR-A is a GPBA receptor agonist. GPBAR-A increases GLP-1 secretion from intestinal cultures.

CAS 63902-38-5 Pinoresinol Diglucoside

Pinoresinol Diglucoside
(CAS: 63902-38-5)

Pinoresinol Diglucoside, one of the major lignans with various pharmacological activities, is a sugar lignan which inhibits α-glucosidase in vitro.

CAS 110140-89-1 Ridogrel

Ridogrel
(CAS: 110140-89-1)

Ridogrel is a thromboxane synthase inhibitor used for the prevention of systemic thrombo-embolism. It is also a receptor antagonist that may be used as an adjun...

Quick Inquiry

Verification code

Featured Items