AM-114 - CAS 856849-35-9
Catalog number: 856849-35-9
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C20H21B2NO5
Molecular Weight:
377.01
COA:
Inquire
Targets:
Proteasome
Description:
AM 114 is an inhibitor of chymotrypsin-like activity of the 20S proteasome. In addition, AM-114 shows anticancer activity, It can inhibit cell growth in human colon cancer HCT116 p53+/+ cells.
Purity:
98%
Appearance:
Powder
Synonyms:
AM-114; AM 114; AM114; Proteasome Inhibitor IX; ((1Z,1'Z)-(1-methyl-4-oxopiperidine-3,5-diylidene)bis(methanylylidene))bis(4,1-phenylene))diboronic acid
Solubility:
Soluble in DMSO
Storage:
-20℃ Freezer
MSDS:
Inquire
Application:
anticancer
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
SRPIKXGUPAKTIZ-APGQMXJTSA-N
InChI:
1S/C20H21B2NO5/c1-23-12-16(10-14-2-6-18(7-3-14)21(25)26)20(24)17(13-23)11-15-4-8-19(9-5-15)22(27)28/h2-11,25-28H,12-13H2,1H3/b16-10-,17-11-
Canonical SMILES:
B(O)(O)c1ccc(cc1)/C=C/2\C(=O)/C(=C\c3ccc(cc3)B(O)O)/CN(C2)C
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