|Description||This active molecular is a selective PI3Kδ inhibitor. PI3Kδ is hyperactivated in B-cell malignancies and plays a vital role in the B-cell receptor pathway. AM-0687 has Cellular potency: pAKT IC50 = 0.7 nM; HWB, u (pAKT) IC 50 = 4.6 nM. AM-0687 shows excellent potency and selectivity profile in biochemical and cellular assays.|
|Solubility||Soluble in DMSO|
|Application||cancer drug candidate|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
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