Alvimopan dihydrate - CAS 170098-38-1
Catalog number: 170098-38-1
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C25H32N2O4.2H2O
Molecular Weight:
460.57
COA:
Inquire
Targets:
Opioid Receptor
Description:
Alvimopan dihydrate is a novel, orally available peripherally restricted opioid antagonist with low systemic absorption. It accelerates the gastrointestinal recovery period with most common side effects in chronic pain patients with OBD were abdominal pai
Publictions citing BOC Sciences Products
  • >> More
Appearance:
Solid powder
Synonyms:
2-[[(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl]amino]acetic acid;dihydrate ADL 8-2698 ADL8-2698 alvimopan alvimopan anhydrous anhydrous alvimopan Entereg LY 246736 LY-246736 LY246736 trans-3,4-dimethyl-4-(3-hydroxyph
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -75℃ for long term (months to years).
MSDS:
Inquire
Shelf Life:
2 years
Quantity:
Grams-Kilos
InChIKey:
USPVLEIQIUNQGE-DBFLIVQGSA-N
InChI:
1S/C25H32N2O4.2H2O/c1-18-16-27(12-11-25(18,2)21-9-6-10-22(28)14-21)17-20(24(31)26-15-23(29)30)13-19-7-4-3-5-8-19;;/h3-10,14,18,20,28H,11-13,15-17H2,1-2H3,(H,26,31)(H,29,30);2*1H2/t18-,20-,25+;;/m0../s1
Canonical SMILES:
CC1CN(CCC1(C)C2=CC(=CC=C2)O)CC(CC3=CC=CC=C3)C(=O)NCC(=O)O.O.O
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Opioid Receptor Products


CAS 189388-22-5 Endomorphin 1

Endomorphin 1
(CAS: 189388-22-5)

Endomorphin 1 is a high affinity (Ki = 360 pM) and highly selective agonist of theμ-opioid receptor with 4000- and 15000-fold preference over δ and κ respective...

CAS 16676-29-2 Naltrexone HCl

Naltrexone HCl
(CAS: 16676-29-2)

Naltrexone significantly suppresses ethanol self-administration and prevents ethanol-induced increases in dialysate dopamine levels.

CAS 58-74-2 Papaverine

Papaverine
(CAS: 58-74-2)

Papaverine is an opiate alkaloid isolated from the plant Papaver somniferum. It is used primarily in the treatment of visceral spasm, vasospasm. It is also used...

CAS 361444-66-8 JDTic

JDTic
(CAS: 361444-66-8)

A 4-phenylpiperidine derivative, for the κ-opioid receptor.

CAS 152685-85-3 Hemorphin-7

Hemorphin-7
(CAS: 152685-85-3)

Hemorphin-7, a hemorphin peptide with antinociceptive and antihypertensive effects, is an endogenous opioid peptide derived from the β-chain of hemoglobin. Hemo...

CAS 1174130-61-0 LY-2456302

LY-2456302
(CAS: 1174130-61-0)

LY-2456302, also called as CERC-501, is a potent, highly selective and centrally-penetrant kappa opioid receptor antagonist(Ki= 0.807 nM)with favorable pharmaco...

BAN ORL 24 dihydrochloride
(CAS: 1401463-54-4)

BAN ORL 24 dihydrochloride is a hydrochloride salt form of BAN ORL 24. BAN ORL 24, a spiro-isobenzofuran compound, has been found to be a NOP receptor antagonis...

CHIR 4531
(CAS: 158198-48-2)

CHIR 4531, an oligopeptides compound, has been found to be an opioid mu receptor agonist and was once studied in pain therapy.

CAS 58569-55-4 Met-Enkephalin

Met-Enkephalin
(CAS: 58569-55-4)

Met-Enkephalin is synthetic opioid peptides that has opioid effects of a relatively short duration.

CAS 170713-75-4 Nociceptin

Nociceptin
(CAS: 170713-75-4)

Nociceptin, a 17 amino acid neuropeptide involved in a variety of biological systems, is the endogenous ligand of the nociceptin receptor, acting as a potent an...

(+)-Igmesine hydrochloride
(CAS: 130152-35-1)

Igmesine is a selective σ1 receptor ligand (KD = 19.1 nM), with nearly no activity at σ2 receptors (IC50 > 1000 nM). It was developed by Pfizer. Igmesine inhibi...

LY 123502
(CAS: 79561-42-5)

LY 123502 is an opioid agonist, but no detailed information has been published yet.

CAS 34552-83-5 Loperamide HCl

Loperamide HCl
(CAS: 34552-83-5)

Loperamide HCl is an opioid-receptor agonist with an ED50 of 0.15 mg/kg.

Lexanopadol
(CAS: 1357348-09-4)

Lexanopadol is a potent Opioid mu receptor agonist originated by Grunenthal. Lexanopadol is suited for the management of moderate to severe chronic pain, includ...

Enadoline hydrochloride
(CAS: 124439-07-2)

Enadolineis a potent selective Opioid kappa receptor agonists originated by Pfizer. However, clinical trials for the treatment of Arrhythmias, Neuroprotection a...

LY2795050
(CAS: 1346133-08-1)

LY2795050, a κ-opioid Receptor antagonist, has been found to be effective in imaging KOR behaving as a PET tracer. IC50: 0.72 nM and 25.8 nM for κ-opioid Recept...

CAS 1108147-88-1 MCOPPB triHydrochloride

MCOPPB triHydrochloride
(CAS: 1108147-88-1)

The trihydrochloride salt form of MCOPPB, an effective full agonist of nociceptin receptor, could be a good antianxiety agent with few side-effects. pKi: 10.07.

CAS 825649-28-3 JNJ 20788560

JNJ 20788560
(CAS: 825649-28-3)

JNJ-20788560 is a delta opioid agonist analgesics. No recent reports of development identified for preclinical development in Inflammatory-pain in USA.

GSK1521498
(CAS: 1007573-18-3)

GSK-1521498 is a novel μ-Opioid receptor antagonist. It shows to attenuate reward-driven compulsive behaviours, such as stimulant drug seeking or binge eating i...

PD-117302
(CAS: 111728-01-9)

PD-117302, a new nonpeptide opioid compound, is a selective kappa-opioid agonist. It has been evaluated in vivo for antinociceptive activity and other effects c...

Chemical Structure

CAS 170098-38-1 Alvimopan dihydrate

Quick Inquiry

Verification code

Featured Items