|Targets||5-HT Receptor | Adrenergic Receptor|
|Description||Alprenolol is a non-selective Beta-Adrenergic receptor and 5-HT1A receptor antagonist for the treatment of angina pectoris.|
|Solubility||Soluble in DMSO|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Boiling Point||383.4ºC at 760mmHg|
Indacaterol is an ultra-long-acting β-adrenoceptor agonist with pKi of 7.36.
Carteolol HCl is a β-adrenoceptor antagonist, used for the treatment of glaucoma.
(R)-6-Hydroxybuspirone is a major active metabolite of Buspirone. (R)-Enantiomer showed higher affinity and selectivity for the 5HT1A receptor compared to the ...
AVN-492 is a novel highly-potent and highly-selective 5-HT6R antagonist. The affinity of AVN-492 to bind to 5-HT6R (Ki = 91 pM) was more than three orders of ma...
Tolazoline is a non-selective competitive α-adrenergic receptor antagonist used in treatment of persistent pulmonary hypertension of the newborn..
Salmeterol is a long-acting beta2-adrenergic receptor (beta 2AR) agonist. It is used clinically in the maintenance and prevention of asthma symptoms and mainten...
AR-08 is an agonist of α2-adrenergic receptor undergone in phase II clinical trials by Arbor Pharmaceuticals for the treatment of attention deficit and hyperac...
Pizotifen Malate is a benzocycloheptane based agent used for recurrent migraine headaches.
Tegaserod maleate is a partial agonist of the 5-HT4 receptor (Ki = 12 nM) that can treat irritable bowel syndrome (IBS).
Alosetron, an effective 5-HT3 receptor antagonist, could be commonly used against irritable bowel syndrome.
B-HT 920 dihydrochloride
Talipexole is a D2 dopamine receptor agonist, displaying anti-Parkinsonian activity.
Olanzapine interacts with key receptors of interest in schizophrenia, having a nanomolar affinity for dopaminergic, serotonergic, alpha 1-adrenergic, and muscar...
Aptazapine is a tetracyclic antidepressant. It was assayed in clinical trials for the treatment of depression in the 1980s but was never marketed. Aptazapine is...
Bromperidol, a derivative of butyrophenone, is an antipsychotic commonly used in the treatment of schizophrenia as it could bind to the D2 dopamine and 5-HT2A s...
Eptapirone, also known as F11440, is a potent agonist of the serotonin (5-HT) receptor subtype 5-HT1A (Ki = 4.8 nM in a radioligand binding assay).
Metaproterenol hemisulfate salt
Metaproterenol hemisulfate salt is the hemisulfate salt form of Metaproterenol, which is a moderately selective beta-adrenergic agonist. It is used in the treat...
Eletriptan is Serotonin 1D receptor agonist originated by Pfizer. It is a second generation triptan drug. It is used as an abortive medication, blocking a migra...
Thesuccinate salt form of Frovatriptan, a carbazole derivative, has been found to be a 5-HT receptor agonist that could be used as an antimigraine agent.
Terazosin is a selective alpha 1 antagonist used for treatment of symptoms of an enlarged prostate (BPH).
Loxapine is a typical antipsychotic medication, used primarily in the treatment of schizophrenia and it is a D2/D4 dopamine receptor antagonist; 5-HT2A/2B, 5-H7...