alpha-Cypermethrin - CAS 67375-30-8
Catalog number: 67375-30-8
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Cypermethrin is a synthetic pyrethroid used as a fast-acting neurotoxin in insects.
> 95%
(±)-Alphamethrin; Aeralfam; Alfazot; Alfoxylate; Alphacypermethrin; Alphaguard; Alphamethrin; Bestox; Centaur; Cismix; Contest; Dominex; Fastac; Fastac Duo; Fendona; Mageos; Ultimate; WL 85871; (1S,3S)-rel-3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic Acid (R)-Cyano(3-phenoxyphenyl)methyl Ester
1.Use of stable carbon isotope ratios to determine the source of cypermethrin in so-called natural plant extract formulations used for organic farming.
Kawashima H1, Kariya T1. Isotopes Environ Health Stud. 2016 Apr 18:1-10. [Epub ahead of print]
Some natural plant extract formulations (NPEFs, also referred to as essential oils) used in organic farming have been shown to contain synthetic pesticides. We obtained samples of four NPEFs (Muso, Hekiro, Kensogen-Ten, and Nurse Green) that were contaminated with the synthetic pyrethroid cypermethrin, and we used gas chromatography coupled with combustion, cryofocusing, and isotope ratio mass spectrometry to determine the stable carbon isotope ratios (δ13C) for the cypermethrin in the four NPEF samples, as well as in ten cypermethrin reagents and two commercial pesticide formulations (Agrothrin emulsion and Agrothrin water-dispersible powder). Our goal was to identify the source of the cypermethrin in the NPEFs. Cryofocusing markedly sharpened the cypermethrin peak and thus improved the accuracy and precision of the determined δ13C values. The δ13C values (± SD) of the 16 cypermethrin samples ranged from -28.3 ± 0.2 to -24.5 ± 0.2 ‰. Surprisingly, the four NPEFs showed similar δ13C values (-26.
2.Toxicities of glyphosate- and cypermethrin-based pesticides are antagonic in the tenspotted livebearer fish (Cnesterodon decemmaculatus).
Brodeur JC1, Malpel S2, Anglesio AB3, Cristos D4, D'Andrea MF3, Poliserpi MB3. Chemosphere. 2016 Apr 29;155:429-435. doi: 10.1016/j.chemosphere.2016.04.075. [Epub ahead of print]
Although pesticide contamination of surface waters normally occurs in the form of mixtures, the toxicity and interactions displayed by such mixtures have been little characterized until now. The present study examined the interactions prevailing in equitoxic and non-equitoxic binary mixtures of formulations of glyphosate (Glifoglex®) and cypermethrin (Glextrin®) to the tenspotted livebearer (Cnesterodon decemmaculatus), a widely distributed South American fish. The following 96 h-LC50s were obtained when pesticide formulations were tested individually: Glifoglex® 41.4 and 53 mg ae glyphosate/L; Glextrin® 1.89 and 2.60 μg cypermethrin/L. Equitoxic and non-equitoxic mixtures were significantly antagonic in all combinations tested. The magnitude of the antagonism (factor by which toxicity differed from concentration addition) varied between 1.37 and 3.09 times in the different non-equitoxic mixtures tested. Antagonism was due to a strong inhibition of cypermethrin toxicity by the glyphosate formulation, the toxicity of the cypermethrin-based pesticide being almost completely overridden by the glyphosate formulation.
3.Behavioral swimming effects and acetylcholinesterase activity changes in Jenynsia multidentata exposed to chlorpyrifos and cypermethrin individually and in mixtures.
Bonansea RI1, Wunderlin DA2, Amé MV3. Ecotoxicol Environ Saf. 2016 Jul;129:311-9. doi: 10.1016/j.ecoenv.2016.03.043. Epub 2016 Apr 7.
The pesticides cypermethrin (CYP) and chlorpyrifos (CPF) were found together in water bodies located in agricultural and urban areas. However, the impact to non-target biota from exposure to mixtures has received little attention. In the current study, we evaluated changes in swimming behavior and cholinesterase enzymes activity in Jenynsia multidentata, to investigate the possible effects of these insecticides individually and in mixtures. Moreover, differences between technical and commercial mixtures of the pesticides were evaluated. Females of J. multidentata were exposed over 96-h to CYP (0.04 and 0.4µgL(-1)), CPF (0.4 and 4µgL(-1)), individually and in a technical and commercial mixtures. Swimming behavior was recorded after 24h and 96h of exposure. Also, we measured cholinesterase enzymes activity in brain and muscle after 96h of exposure. Exposure to CYP increased the exploratory activity of J. multidentata in the upper area of the aquarium.
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CAS 67375-30-8 alpha-Cypermethrin

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