alpha-Amanitin - CAS 23109-05-9
Catalog number:
23109-05-9
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C39H54N10O14S
Molecular Weight:
918.97
COA:
Inquire
Targets:
ADCs Cytotoxin
Description:
alpha-Amanitin, the major toxic bicyclic octapeptide of the mushroom Amanita phalloides, inhibits RNA polymerase II at 1 µg/ml, RNA polymerase III at 10 µg/ml and RNA polymerase IV at 50 µg/ml.
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Purity:
95%
Appearance:
White to light yellow
Synonyms:
alpha-amanitin alpha-Amanitin, Amanita sp. alpha-Amanitine Amanitin 2-[29-(butan-2-yl)-21-(3,4-dihydroxybutan-2-yl)-2,14-dihydroxy-11-oxido-5,8,20,23,24,27,30,33-octaoxo-1,2,3,5,6,7,8,9,10,12,17,18,19,20,21,22,23,23a-octadecahydro-9,18-(epiminoethanoimino
Solubility:
Soluble to 5 mM in ethanol and to 5 mM in water
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -92℃ for long term (months to years).
MSDS:
Inquire
Shelf Life:
2 years
Quantity:
Data not available, please inquire.
Boiling Point:
1622.2ºC at 760 mmHg
Melting Point:
254-255ºC(lit.)
Density:
1.57 g/cm3
InChIKey:
CIORWBWIBBPXCG-UHFFFAOYSA-N
InChI:
1S/C39H54N10O14S/c1-4-16(2)31-36(60)42-11-29(55)43-25-15-64(63)38-21(20-6-5-18(51)7-22(20)46-38)9-23(33(57)41-12-30(56)47-31)44-37(61)32(17(3)27(53)14-50)48-35(59)26-8-19(52)13-49(26)39(62)24(10-28(40)54)45-34(25)58/h5-7,16-17,19,23-27,31-32,46,50-53H,4,8
Canonical SMILES:
CCC(C)C1C(=O)NCC(=O)NC2CS(=O)C3=C(CC(C(=O)NCC(=O)N1)NC(=O)C(NC(=O)C4CC(CN4C(=O)C(NC2=O)CC(=O)N)O)C(C)C(CO)O)C5=C(N3)C=C(C=C5)O
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CAS 23109-05-9 alpha-Amanitin

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