|Description||The hydrochloride salt form of Alosetron, a 5HT3-receptor antagonist, could be used against bowel syndrome.|
|Synonyms||GR 68755; GR 68755X; Lotronex; GR-68755; GR68755|
|Solubility||10 mM in DMSO|
|Application||The hydrochloride salt form of Alosetron is a 5HT3-receptor antagonist that could be used against bowel syndrome.|
|Shelf Life||As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly|
LY 344864 is a brain penetrant, full agonist that specifically targets 5-HT1F receptor (pKi = 8.2) with > 80-fold selectivity over other serotonin receptors (Ki...
The maleic acid salt form of Alosetron which is an effective 5-HT3 receptor antagonist and could be commonly used against irritable bowel syndrome.
Naratriptan is a triptan agent that is used for the treatment of migraine headaches.
Almotriptan, also called as Almogran, is a agonist with high and specific affinity for 5-HT1B/1D receptors. developed by Almirall Prodesfarma for the acute trea...
Alverine Citrate is a highly potent competitive CXCR4 antagonist with EC50 of 0.3 nM.
Asenapine hydrochloride, also called Org 5222 and HSDB 8061, shows high affinity for numerous receptors including 5-HT receptor and adrenergic receptor. (pKi: 5...
The citrate salt form of tandospirone, a partial 5HT1A receptors agonist, could be effective as an antianxiety and antidepressant agent.
BRL 54443 is a 5-HT1E and 5-HT1F receptor agonist with pKi of 8.7 and 9.25, respectively, with a weak binding affinity for 5-HT1A, 5-HT1B, 5-HT1D receptors.
Ziprasidone hydrochloride monohydrate
The hydrochloride monohydrate salt form of Ziprasidone, a benzothiazol derivative, has been found to be a 5HT2A and D2 receptor antagonist that could be used ag...
MK212 hydrochloride is a selective 5-HT2C serotonin receptor agonist. It displays selectivity for 5-HT2C over 5-HT2A with IC50 values of 0.028 and 0.42 μM for h...
Naftidrofuryl, being useful in enhancing cellular oxidative, could be used as a vasodilator in the treatment of peripheral and cerebral vascular disorders.
5HT6-ligand-1 is a potent 5-HT6 receptor ligand (Ki= 1.43 nM).
The hydrobromide salt form of NAN-190 which is an effective antagonist of 5-HT1A serotonin receptor.
Methysergide is an ergot derivative that is a congener of lysergic acid diethylamide for the treatment of vascular headache
PR-073 is a novel 5-HT7 antagonist, which can inhibit immune responses and treat inflammatory bowel disease (IBD). Preclinical studies demonstrated that PR-073 ...
Adinazolam, a triazolobenzodiazepine, a high affinity for β-adrenoceptors (Kd = 0.061 nM) and alters the expression of serotonin 5-HT2 receptors in rat fronto-p...
MK212 is a 5HT2C-receptor agonist. It exhibited anxiolytic activity in mice at low doses. It is a serotonin agonist. It could promote the secretion of serum pro...
LY 215840 is a potent antagonist of both Serotonin 2A receptor and Serotonin 7 receptor. It can reduce stimulatory effect of serotonin on aldosterone secretion ...
Piboserod is a highly and potent selective 5-HT4 receptor antagonist which as been studied in vitro as well as in vivo as a pharmacological tool to evaluate the...
SB-242084 HCl salt
SB-242084 is a psychoactive drug and research chemical which acts as a selective antagonist for the 5HT2C receptor. It can increase the effectiveness of the sel...