Alibendol - CAS 26750-81-2
Catalog number: 26750-81-2
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
Molecular Weight:
Alibendol is an antispasmodic,choleretic, and cholekinetic.
Publictions citing BOC Sciences Products
  • >> More
EB 1856
1. A sensitive, acetonitrile-free, HPLC method for determination of alibendol in dog plasma and its application to pharmacokinetic studies
Jae Kuk Ryu. Journal of Pharmaceutical Investigation (2012) 42:185–190
Alibendol, or 5-allyl-2-hydroxy-N-(2-hydroxyethyl)-3-methoxybenzamide, is known as an active pharmaceutical ingredient in antispasmodic, choleretic, and cholekinetic medications. This drug is useful for the treatment of dyspepsia due to biliary insufficiency, alimentary intolerance,and constipation of hepatic origin (Kim et al. 2004; Song et al. 2010). To date, only one method to assess alibendol levels in plasma has been reported in the literature (Song et al. 2010). However, this method uses acetonitrile as a mobile phase. Because acetonitrile is obtained as a co-product in the production of acrylonitrile, many industries are experiencing a shortage of acetonitrile (Venkatasami and Sowa 2010). This ongoing acetonitrile shortage has forced chemists to replace acetonitrile with more readily available solvents, such as methanol. To date, this is the first report of an acetonitrile-free high performance liquid chromatography (HPLC) method for the determination of alibendol in biological fluids. The method previously reported by Song et al. (2010) achieved an LLOQ of 50 ng/ml. Thus, that method may lack the sensitivity needed to determine the low plasma concentrations encountered in pharmaco- kinetic studies. Furthermore, that report is written in Korean, so it may be difficult for non-Koreans to use that method.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Products

CAS 2310-17-0 Phosalone

(CAS: 2310-17-0)

Phosalone can be used as insecticide and acaricide.

CAS 5915-41-3 Terbuthylazine

(CAS: 5915-41-3)

Terbuthylazine is a triazine herbicide.

CAS 68278-23-9 Eflornithine hydrochloride

Eflornithine hydrochloride
(CAS: 68278-23-9)

Eflornithine hydrochloride is a drug found to be effective in the treatment of facial hirsutism. It is a "suicide inhibitor," irreversibly binding to Ornithine ...

CAS 600-57-7 11beta-Hydroxyprogesterone

(CAS: 600-57-7)

11beta-Hydroxyprogesterone is a potent inhibitors of 11β-Hydroxysteroid dehydrogenase and can confer mineralocorticoid activity on corticosterone in the rat in ...

(CAS: 31896-92-1)

PYR-6921is a useful intermediate for chemical synthesis of biologically molecules.

(CAS: 1379686-30-2)

SR9009, an analogue of SR9011, has similar effect for having probable effect against sleep disorders and metabolic diseases. IC50: 670 nM and 800 nM for Rev-Erb...

CAS 702681-67-2 CP-868388

(CAS: 702681-67-2)

CP-868388 is a bio-active chemical, but detailed information has not been published.

CAS 14087-31-1 Gaxilose

(CAS: 14087-31-1)

Gaxilose is a synthetic disaccharide and a substrate of intestinal lactase. It can be applicated in a new noninvasive diagnostic test based on urine or serum me...

SV40 large T antigen NLS

SV40 large T antigen NLS, a hexamer protein generated from Large T antigen residue 47 to 55, enables protein import into cell nucleus.

(CAS: 400044-47-5)

UK‑396082 is an activated thrombin activatable fibrinolysis inhibitor(Ki = 10 nM), exhibited antithrombotic efficacy in a rabbit model of venous thrombosis, yet...

PD 136450
(CAS: 139067-52-0)

PD-136,450 is a Cholecystokinin type B receptor antagonist originated by Pfizer. It is a partial secretory agonist in the stomach and a full agonist in the panc...

CAS 33342-05-1 Gliquidone

(CAS: 33342-05-1)

Gliquidone is an ATP-sensitive K+ channel antagonist with IC50 of 27.2 nM.

CAS 115810-12-3 Tubeimoside II

Tubeimoside II
(CAS: 115810-12-3)

Tubeimoside II is a natural analogue of oleanane type of triterpenoid saponin, showing anti-inflammatory, antitumor, and antitumor-promoting effects.

SLLK, Control Peptide for TSP1 Inhibitor

SLLK, Control Peptide for TSP1 Inhibitor is a control peptide for LSKL (leucine-serine-lysine-leucine). C-terminus is amidated.

CAS 86541-74-4 Benazepril HCl

Benazepril HCl
(CAS: 86541-74-4)

Benazepril is a drug of the angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure.

CAS 81720-08-3 Rehmannioside D

Rehmannioside D
(CAS: 81720-08-3)

Rehmannioside D is a carotenoid glycoside extracted from the roots of Rehmannia glutinosa.

(CAS: 4026-95-3)

Botanical Source from Bufo bufo gargarizans and Bufo formosus, used for microbial transformation.

(CAS: 101183-99-7)

CK-2289 is an type III cyclic 3'5'-adenosine monophosphate phosphodiesterase inhibitor. It may be used in the treatment of congestive heart failure.

CAS 21059-46-1 Aspartic acid calcium

Aspartic acid calcium
(CAS: 21059-46-1)

Aspartic acid calcium is a chelate where calcium is attached to L-Aspartic acid, an amino acid that is used in the biosynthesis of proteins

CAS 1323403-33-3 Iberdomide

(CAS: 1323403-33-3)

Iberdomide, also known as CC-220, is a modulator of cereblon potentially for the treatment of systemic lupus erythematosus. Iberdomide exhibits an IC50 of 60 nM...

Chemical Structure

CAS 26750-81-2 Alibendol

Quick Inquiry

Verification code

Featured Items