|Description||Alemtuzumab is a humanized monoclonal antibody that is used as a drug for the treatment of chronic lymphocytic leukemia (CLL), cutaneous T-cell lymphoma (CTCL), T-cell lymphoma as well as multiple sclerosis. It acts via binding to CD52 which exist on the surface of mature lymphocytes. Alemtuzumab was approved as a second-line therapy for CLL.|
|Brife Description||CD52, CLL, CTCL, T-cell lymphoma, multiple sclerosis, second-line therapy for CLL|
|Sequence||1 QVQLQESGPG LVRPSQTLSL TCTVSGFTFT DFYMNWVRQP PGRGLEWIGF
51 IRDKAKGYTT EYNPSVKGRV TMLVDTSKNQ FSLRLSSVTA ADTAVYYCAR
101 EGHTAAPFDY WGQGSLVTVS SASTKGPSVF PLAPSSKSTS GGTAALGCLV
151 KDYFPEPVTV SWNSGALTSG VHTFPAVLQS SGLYSLSSVV TVPSSSLGTQ
201 TYICNVNHKP SNTKVDKKVE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK
251 PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY
301 NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP
351 QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP
401 VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG
|Synonyms||Alemtuzumab (usan/inn); Campath (tn); D02802; MabCampath|
|Application||the treatment of chronic lymphocytic leukemia (CLL), cutaneous T-cell lymphoma (CTCL), T-cell lymphoma as well as multiple sclerosis|
|Shelf Life||2 years|
|Quantity||Data not available, please inquire.|
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