|Description||A neutral linear peptaibol complex with potent antibiotic activity, containing 20 “amino acids” With an acetyl and phenylalaninol termini, produced by trichoderma sp; an ionopohore, transporting ions through membranes and artificial lipid membranes; forms voltage-dependent ion channels in lipid bilayer membranes|
|Purity||>98% by HPLC|
|Synonyms||Alamethicin F, Alamethicin Rf 50, Atroviridin A, 18-L-Glutamine-alamethicin I|
|Solubility||Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.|
A hydrophobic cyclic peptide isolated from several fungal species including cylindrocarpon, fusarium, trichoderma and tolypocladium; inhibits T-cell activation;...
A minor analogue of the cyclosporin family which is only weakly immunologically active; a potent inhibitor of tumour-promoting phorbol esters on mouse skin in v...
A closely related co-metabolite of cyclosporin A; possesses no immunosuppressant activity and has found use as a control to determine the role of immunosuppress...
A minor analogue of the cyclosporin family which is immunologically inactive as it does not bind to immunophilin; the most extensively investigated of the minor...
A minor analogue of the cyclosporin complex produced by a number of different fungal genera including trichoderma, tolypocladium, fusarium, nectria and acremoni...
Alamethicin, an antibiotic peptide compound, could be obtained from the fungus Trichoderma viride and is commonly used in studing ion channel assembly and pepti...
A neutral linear peptaibol complex with potent antibiotic activity, containing 20 “amino acids” With an acetyl and phenylalaninol termini, produced by trichoder...
A minor analogue of the cyclosporin complex produced by a number of fungal species, including trichoderma, tolypocladium, fusarium, nectria and acremonium; poss...
A rearranged degradation product formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions