AK-7 - CAS 420831-40-9
Catalog number: 420831-40-9
Category: Inhibitor
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Molecular Formula:
C19H21BrN2O3S
Molecular Weight:
437.35
COA:
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Targets:
Sirtuin
Description:
AK-7 is a selective and brain-permeable SIRT2 inhibitor, which displays no effect on SIRT1 or SIRT3. It could decrease neuronal cholesterol levels and improve motor function and ameliorates brain atrophy in a mouse model of Huntington's disease.
Purity:
>98%
MSDS:
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InChIKey:
IYAYHZZWYNXHEQ-UHFFFAOYSA-N
InChI:
InChI=1S/C19H21BrN2O3S/c20-16-8-6-9-17(14-16)21-19(23)15-7-5-10-18(13-15)26(24,25)22-11-3-1-2-4-12-22/h5-10,13-14H,1-4,11-12H2,(H,21,23)
Canonical SMILES:
C1CCCN(CC1)S(=O)(=O)C2=CC=CC(=C2)C(=O)NC3=CC(=CC=C3)Br
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