AK-1 - CAS 330461-64-8
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C19H21N3O5S
Molecular Weight:
403.45
COA:
Inquire
Targets:
Sirtuin
Description:
AK-1 is a potent, specific and cell-permeable SIRT2 inhibitor (IC50= 12.5 μM) with excellent selectivity against SIRT1 and SIRT3 (IC50 >50 μM, and >50 μM for SIRT1 and SIRT3 respectively).
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Brife Description:
A potent, selective and cell-permeable SIRT2 inhibitor (IC50= 12.5 μM)
Synonyms:
3-(azepan-1-ylsulfonyl)-N-(3-nitrophenyl)benzamide; SIRT2 Inhibitor II, AK-1; SIRT2 Inhibitor II; CHEMBL1797749; 3-(azepan-1-ylsulfonyl)-N-(3-nitrophenyl)benzamide
Solubility:
DMSO
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Density:
1.375±0.06 g/cm3
InChIKey:
HAYBKCHPEBZNGW-UHFFFAOYSA-N
InChI:
1S/C19H21N3O5S/c23-19(20-16-8-6-9-17(14-16)22(24)25)15-7-5-10-18(13-15)28(26,27)21-11-3-1-2-4-12-21/h5-10,13-14H,1-4,11-12H2,(H,20,23)
Canonical SMILES:
C1CCCN(CC1)S(=O)(=O)C2=CC=CC(=C2)C(=O)NC3=CC(=CC=C3)[N+](=O)[O-]
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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Chemical Structure

CAS 330461-64-8 AK-1

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