AHU-377 - CAS 149709-62-6
Catalog number:
B0084-458470
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C24H29NO5
Molecular Weight:
411.49
COA:
Inquire
Targets:
Neprilysin
Description:
Sacubitril, also known as AHU377 or LCZ696, is angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. LBQ657 inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptide, two blood pressure lowering peptides that work mainly by reducing blood volume.
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Purity:
>98%
Synonyms:
Sacubitril; AHU 377; AHU377
MSDS:
Inquire
Application:
For research used only
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