AGN 196996 - CAS 958295-17-5
Catalog number: 958295-17-5
Category: Inhibitor
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Molecular Formula:
C24H20BrNO5
Molecular Weight:
482.32
COA:
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Targets:
RAR/RXR
Description:
AGN 196996 is a potent and selective antagonist of RARα. It has been reported to selectively bind to RARs (retinoic acid receptors) for RARα, RARβ and RARγ. It can inhibit the gene transcription activity which induced by ATRA and other RAR agonists. It shows no activity in transactivation assays, but instead block the gene transcriptional activity induced by ATRA and other RAR agonists.
Purity:
>98%
MSDS:
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InChIKey:
BUGXGZOGQGUTBC-UHFFFAOYSA-N
InChI:
InChI=1S/C24H20BrNO5/c1-3-31-22-19(21(27)15-6-4-14(2)5-7-15)12-17(13-20(22)25)23(28)26-18-10-8-16(9-11-18)24(29)30/h4-13H,3H2,1-2H3,(H,26,28)(H,29,30)
Canonical SMILES:
CCOC1=C(C=C(C=C1Br)C(=O)NC2=CC=C(C=C2)C(=O)O)C(=O)C3=CC=C(C=C3)C
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CAS 958295-17-5 AGN 196996

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