|Description||Fabomotizole (brand name Afobazole) is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Clinical trials have shown fabomotizole to be well tolerated and reasonably effective for the treatment of anxiety. Experiments of mice have showed antimutagenic and antiteratogenic properties.|
|B0084-458641||5 mg||$178||In stock|
|Synonyms||CM346; Afobazol; Fabomotizole; CM 346; CM-346|
Sufugolix, also known as TAK-013, is a highly potent, non-peptide and orally available luteinizing hormone-releasing hormone (LHRH) receptor antagonist with an ...
Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall.Paeoniflorin has antiandrogenic properties. Paeoniflorin inhibits the pro...
Parathyroid hormone (1-34) (human)
Parathyroid hormone (1-34) (human) is a fragment of human parathyroid hormone (hPTH) peptide sequence containing the 34 N-terminal residues of hPTH. PTH 1-34 in...
Lonidamine is a derivative of indazole-3-carboxylic acid, which for a long time, has been known to inhibit aerobic glycolysis in cancer cells. It seems to enhan...
AAI101 is a novel β-lactamase inhibitor with activity against extended-spectrum β-lactamases (ESBL), as well as, some class A and class D carbapenemases.
A selective inhibitor of calcineurin-mediated dephosphorylation of nuclear factor of activated T cells (NFAT)
Clortermine hydrochloride is a new non-amphetamine anorexigenic agent. It is used as an anti-obesity drug.
RR-src is a peptide tyrosine kinase substrate derived from the phosphorylation site of pp60(Src). It is used to monitor purification of insulin receptor and to ...