AF38469 - CAS 1531634-31-7
Catalog number: 1531634-31-7
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C15H11F3N2O3
Molecular Weight:
324.25
COA:
Inquire
Targets:
Others
Description:
AF38469 is a novel, selective, orally bioavailable Sortilin inhibitor and showed no inhibition or stimulation of >50% at 10μM in a standard selectivity panel of ca. 70 targets run at CEREP. AF38469 showed no activity against the NTR1 receptor. In addition
Appearance:
Solid powder
Synonyms:
2-[(6-methylpyridin-2-yl)carbamoyl]-5-(trifluoromethyl)benzoic acid CHEMBL3098745 AF38469 4n7e SCHEMBL15903106 BDBM50445054 ZINC95921158 HY-12802 KB-274741 n-(6-methylpyridin-2-yl)-5-trifluoromethyl-phthalamic acid
Solubility:
Soluble to ≥ 43 mg/mL in DMSO
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -63℃ for long term (months to years).
MSDS:
Inquire
Shelf Life:
2 years
Quantity:
Grams-Kilos
Boiling Point:
392.3±42.0 °C | Condition: Press: 760 Torr
Density:
1.448±0.06 g/cm3
InChIKey:
JWCUSQCZMQIBMR-UHFFFAOYSA-N
InChI:
1S/C15H11F3N2O3/c1-8-3-2-4-12(19-8)20-13(21)10-6-5-9(15(16,17)18)7-11(10)14(22)23/h2-7H,1H3,(H,22,23)(H,19,20,21)
Canonical SMILES:
CC1=NC(=CC=C1)NC(=O)C2=C(C=C(C=C2)C(F)(F)F)C(=O)O
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