|Description||AF38469 is a novel, selective, orally bioavailable Sortilin inhibitor and showed no inhibition or stimulation of >50% at 10μM in a standard selectivity panel of ca. 70 targets run at CEREP. AF38469 showed no activity against the NTR1 receptor. In addition|
|Synonyms||2-[(6-methylpyridin-2-yl)carbamoyl]-5-(trifluoromethyl)benzoic acid CHEMBL3098745 AF38469 4n7e SCHEMBL15903106 BDBM50445054 ZINC95921158 HY-12802 KB-274741 n-(6-methylpyridin-2-yl)-5-trifluoromethyl-phthalamic acid|
|Solubility||Soluble to ≥ 43 mg/mL in DMSO|
|Storage||Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -63℃ for long term (months to years).|
|Shelf Life||2 years|
|Boiling Point||392.3±42.0 °C | Condition: Press: 760 Torr|
DS-1040 inhibits the activated form of thrombin-activatable fibrinolysis inhibitor (TAFIa), used for the treatment of acute ischemic stroke (AIS). DS-1040 subst...
FH1 (BRD-K4477) is a small molecule, which promotes the maturation and differentiation of induced pluripontent stem cells (iPSCs) to hepatocytes. FH 1 treatment...
FMK 9a is a covalent autophagin-1 inhibitor (IC50= 80 and 73 μM in FRET and LRA assay).
HLCL65 hydrochloride is a first-in-class inhibitor of PRMT5. HLCL65 selectively inhibits Th1 cell proliferation (IC50 value 1.1 μM). In vivo, HLCL65 suppresses ...
ABT116 is an antagonist of transient receptor potential vanilloid type 1.
Kisspeptin-10, also called as Metastin (45-54), is a potent vasoconstrictor and a potent endogenous ligand for the Kisspeptin receptor (KISS1, GPR54).
Artemotil is a fast acting blood schizonticide. It is a semi-synthetic derivative of artemisinin, which is a natural product of the Chinese plant Artemisia annu...
This active molecular has a para-benzoquinone structure and was developed for inherited mitochondrial diseases base on vitamin E. The mechanism of action of Vat...
This active molecular is a potent cephalosporin antibiotic with a catechol moiety on the 3-position side chain under the development of Shionogi. Cefiderocol ex...
Sodium Molybdate, anhydrous
Sodium molybdate is used as source of molybdate and it is often used in the form of Sodium molybdate dihydrate. It inactivated both the active and inactive form...
Brotianide, with anti-fasciolidal activity, is an anthelminthic drug for the treatment of severe infections on animals to remove larvae.
Glisoxepide, a second-generation sulfonylurea, exerts greater binding affinity than the first-generation compounds. With antihyperglycemic activity, Glisoxepide...
This active molecular is a guanidinium antihypertensive agent through adrenergic neuron-blocking.
Kaempferol is a natural flavonol, a type of flavonoid, that has been isolated from plant sources.
Extract from Aconitum carmichaeli Debx.
Epimedin B, a flavonoids natural product extracted from Herbal Epimedium, has been studied to have potential antiosteoporotic effect.
IKarisoside A is a natural compound isolated from Epimedium koreanum, which has anti-inflammatory properties.
ECMS is a useful protective group in antibody drug conjugates as a ADCs Linker.
Fenoxaprop-P-ethyl is a post-emergent phenoxy herbicide for control of postemergence annual grasses in crop fields.
AG-5507 is a bio-active chemical howerver, its detailed information has not been published.