| Molecular Formula: | |
|---|---|
| Molecular Formula | C15H11F3N2O3 |
| Molecular Weight: | |
| Molecular Weight | 324.25 |
| COA: | |
| COA | Inquire |
| Targets: | |
| Targets | Others |
| Description: | |
| Description | AF38469 is a novel, selective, orally bioavailable Sortilin inhibitor and showed no inhibition or stimulation of >50% at 10μM in a standard selectivity panel of ca. 70 targets run at CEREP. AF38469 showed no activity against the NTR1 receptor. In addition |
| Appearance: | |
|---|---|
| Appearance | Solid powder |
| Synonyms: | |
| Synonyms | 2-[(6-methylpyridin-2-yl)carbamoyl]-5-(trifluoromethyl)benzoic acid CHEMBL3098745 AF38469 4n7e SCHEMBL15903106 BDBM50445054 ZINC95921158 HY-12802 KB-274741 n-(6-methylpyridin-2-yl)-5-trifluoromethyl-phthalamic acid |
| Solubility: | |
| Solubility | Soluble to ≥ 43 mg/mL in DMSO |
| Storage: | |
| Storage | Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -63℃ for long term (months to years). |
| MSDS: | |
| MSDS | Inquire |
| Shelf Life: | |
| Shelf Life | 2 years |
| Quantity: | |
|---|---|
| Quantity | Grams-Kilos |
| Boiling Point: | |
| Boiling Point | 392.3±42.0 °C | Condition: Press: 760 Torr |
| Density: | |
| Density | 1.448±0.06 g/cm3 |
| InChIKey: | |
| InChIKey | JWCUSQCZMQIBMR-UHFFFAOYSA-N |
| InChI: | |
| InChI | 1S/C15H11F3N2O3/c1-8-3-2-4-12(19-8)20-13(21)10-6-5-9(15(16,17)18)7-11(10)14(22)23/h2-7H,1H3,(H,22,23)(H,19,20,21) |
| Canonical SMILES: | |
| Canonical SMILES | CC1=NC(=CC=C1)NC(=O)C2=C(C=C(C=C2)C(F)(F)F)C(=O)O |
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