|Description||AEG 3482 has been found to be an inhibitor of c-jun N-terminal kinase (JNK) signaling and could probably be useful against some neurological disorders.|
|Purity||≥99% by HPLC|
|Appearance||Light Yellow Solid|
AEG 3482 has been found to be an inhibitor of c-jun N-terminal kinase (JNK) signaling and could probably be useful against some neurological disorders.
JNK-IN-8 inhibits c-Jun phosphorylation in HeLa and A375 cells with EC50 of 486 nM and 338 nM, respectively.
SP-600125 is a specific JNK inhibitor. SP600125 kills p53-deficient cells more efficiently than their p53-proficient counterparts, in vitro. Similar observation...
AS601245 is a JNK Inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively.
ATP-competitive, selective JNK inhibitor. Decreases c-Jun transcription activity and proliferation. Decreases cytochrome c release and caspase 3 activation. Sho...
SR-3306, an aminopyrimidine derivative, is a JNK Inhibitor and could be mainly active in Phosphorylation & Dephosphorylation actions.
CC 401 dihydrochloride is a potent JNK inhibitor (Ki = 25-50 nM). CC 401 competitively binds to ATP-binding site of phosphorylated JNK to inhibit JNK.
IQ 1S is a c-Jun N-terminal kinase (JNK) inhibitor. It inhibits the production of nitric oxide in vitro and inhibits the release of nitric oxide upon metabolism...