ADX88178 - CAS 1235318-89-4
Catalog number:
1235318-89-4
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C12H12N6S
Molecular Weight:
272.33
COA:
Inquire
Targets:
Metabotropic Glutamate Receptor 4
Description:
This active molecular is a selectiveMetabotropic glutamate receptor 4 agonist and modulator under the development of Addex Therapeutics. In the marble burying test, ADX88178 can reduce the number of buried marbles Meanwhile, in the EPM (elevated plus maze) test, it can also increase open-arm exploration, indicative of anxiolytic-like efficacy. Now, preclinical trials for Anxiety disorders, Cocaine abuse, Multiple sclerosis and Parkinson's diseas were on-going.
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Purity:
98%
Appearance:
Powder
Synonyms:
SCHEMBL369060; GTPL6238; 5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)-1,3-thiazol-2-amine
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
Anxiety disorders; Cocaine abuse; Multiple sclerosis; Parkinson's disease
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
MIQNXKWDQRNHAU-UHFFFAOYSA-N
InChI:
InChI=1S/C12H12N6S/c1-7-3-4-13-11(16-7)18-12-17-10(8(2)19-12)9-5-14-15-6-9/h3-6H,1-2H3,(H,14,15)(H,13,16,17,18)
Canonical SMILES:
CC1=NC(=NC=C1)NC2=NC(=C(S2)C)C3=CNN=C3
Current Developer:
Addex Therapeutics
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ADX88178
(CAS: 1235318-89-4)

This active molecular is a selectiveMetabotropic glutamate receptor 4 agonist and modulator under the development of Addex Therapeutics. In the marble burying t...

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