|Description||AdTx1 is a high affinity, selective and non-competitive α1A adrenoceptor antagonist with Ki value of 0.35 nM. It is a 65 amino-acid peptide originally isolated from the venom of the green mamba. It is stabilized by four disulfide bridges and belongs to the family of the three-finger-fold peptide. It displays no significant activity against a range of other GPCRs. It antagonizes effects of phenylephrine on intra-urethral pressure in rats and on isolated rabbit prostate muscle in vitro. It is used as a potent relaxant of smooth muscles.|
Propranolol Hydrochloride is a β-adrenergic antagonist used to treat high blood pressure, a number of types of irregular heart rate, thyrotoxicosis, capillary h...
3-MPPI is a very potent ligand for α1 sites (Ki for displacement of prazosin = 0.2 nM) and regulates smooth muscle contraction. 3-MPPI shows different binding p...
Mirabegron (formerly YM-178, trade name Myrbetriq) is a drug for the treatment of overactive bladder. It was developed by Astellas Pharma and was approved in th...
B-HT 933 dihydrochloride
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Sunepitron hydrochloride is a potent and selective serotonin 5-HT1A autoreceptor agonist, α2-adrenergic antagonist, and dopamine D2 agonist. The phase III clini...
Amezinium methylsulfate, a sympathomimetic drug used for the treatment of low blood pressure, increases the arterial blood pressure and heart rate of anaestheti...
Landiolol is an ultra-short-acting Beta 1 adrenergic receptor antagonist using for managing supraventricular tachyarrhythmias in sepsis. It is also used as an a...
Arbutamine is β-adrenergic receptor originated by SICOR. It is a cardiac stimulant. Arbutamine is a synthetic catecholamine with positive chronotropic and inotr...