|Description||Adoprazine, also known as SLV 313, with potential antipsychotic property, is a agonist of cloned h5-HT(1A) receptors (pEC(50)=9.0) and a full antagonist of hD(2) (pA(2)=9.3) and hD(3) (pA(2)=8.9) receptors.|
|Appearance||Light yellow to yellow solid|
|Synonyms||1-(2,3-dihydro-1,4-benzodioxin-5-yl)-4-[[5-(4-fluorophenyl)pyridin-3-yl]methyl]piperazine 1-(2,3-dihydro-1,4-benzodioxin-5-yl)-4-((5-(4-fluorophenyl)-3-pyridinyl)methyl)piperazine SLV 313 SLV-313 SLV313|
|Solubility||Soluble in DMSO|
|Storage||Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -79℃ for long term (months to years).|
|Shelf Life||2 years|
|Quantity||Data not available, please inquire.|
|Boiling Point||565.0±50.0 °C | Condition: Press: 760 Torr|
Naftidrofuryl, being useful in enhancing cellular oxidative, could be used as a vasodilator in the treatment of peripheral and cerebral vascular disorders.
The hydrochloride salt form of Agomelatine that is an antidepressant agent for acting as an antagonism of the 5-HT2C receptor. It is also an antagonist of 5-HT2...
Tianeptine is a selective facilitator of 5-HT uptake in vitro and in vivo with psychostimulant, anti-ulcer and anti-emetic properties.
The hydrochloride salt form of Alosetron, a 5HT3-receptor antagonist, could be used against bowel syndrome.
PRX 08066, a selective 5-hydroxytryptamine receptor 2B(5-HT2BR) antagonist, causes selective vasodilation of pulmonary arteries. Its IC50 value is 3.4 nM. It ca...
Eltoprazine belongs the phenylpiperazine class which is a serenic or antiaggressive agent. It acts as an agonist at the 5-HT1A and 5-HT1B receptors and as an an...
Vortioxetine is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, r...
(S)-6-Hydroxybuspirone is a major active metabolite of Buspirone. (R)-Enantiomer showed higher affinity and selectivity for the 5HT1A receptor compared to the ...
LY310762 has a higher affinity for the guinea pig 5-HT1D receptor than for the 5-HT1B receptor. LY310762 potentiates the potassium-induced [3H]5-HT outflow from...
Lintopride, also called as ACEMM, a new benzamid, is a 5HT4 antagonist with moderate 5HT3 antagonist properties that increases gastric emptying, stimulates antr...
The tosylate salt form of Lumateperone which is an highly effective antagonist of 5-HT2A receptor, could be used against insomnia. IC50: 0.54 nM(Ki).
5HT6-ligand-1 is a potent 5-HT6 receptor ligand (Ki= 1.43 nM).
Mosapride, a selective agonist of 5-HT4 receptor, could be used as a astroprokinetic agent. It is also found to be a 5-HT3 receptor antagonist.
Cisapride is a drug that increases motility in the upper gastrointestinal tract and is used as a Gastroprokinetic. It acts directly as a serotonin 5-HT4 recepto...
MIN-101, a novel cyclic amide derivative, is a 5-HT2A and sigma 2 receptor antagonist (Ki= 7.53 nM for 5-HT2A and 8.19 nM for sigma-2, respectively).
Quetiapine Fumarate is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression.
Agomelatine L(+)-Tartaric acid
Agomelatine L(+)-Tartaric acid is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor. It is used as an ant...
5-HT2 antagonist 1
A potent antagonist of 5-HT2 receptor
Tropisetron is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor. It is used mainly as a...