AdipoRon hydrochloride - CAS 1781835-20-8
Category: Inhibitor
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Molecular Formula:
C27H29N2O3Cl
Molecular Weight:
464.98
COA:
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Targets:
Adiponectin Receptor
Description:
AdipoRon hydrochloride is the hydrochloride salt and water-soluble derivative of AdipoRon, which is a potent and selective agonist of adiponectin receptors AdipoR1 and AdipoR2 with Kd values of 1.8 and 3.1 μM respectively. It activates PPAR-α and AMPK pathways in the liver and muscle. It ameliorates dyslipidemia, insulin resistance and glucose intolerance in db/db mice. It is a promising treatment for obesity-related diseases such as type 2 diabetes. It is orally active antidiabetic agent.
Purity:
≥98% by HPLC
Synonyms:
2-(4-Benzyoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]acetamide hydrochloride
MSDS:
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InChIKey:
TZVJQEGKRLDTHQ-UHFFFAOYSA-N
InChI:
InChI=1S/C27H28N2O3.ClH/c30-26(28-24-15-17-29(18-16-24)19-21-7-3-1-4-8-21)20-32-25-13-11-23(12-14-25)27(31)22-9-5-2-6-10-22;/h1-14,24H,15-20H2,(H,28,30);1H
Canonical SMILES:
C1CN(CCC1NC(=O)COC2=CC=C(C=C2)C(=O)C3=CC=CC=C3)CC4=CC=CC=C4.Cl
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Chemical Structure

CAS 1781835-20-8 AdipoRon hydrochloride

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