|Description||Adiphenine HCl is a nicotinic receptor inhibitor with IC50 of 15 μM, used as an antispasmodic drug.|
AZD 0328 is a potent α7 NNR/5HT3 receptor agonist. AZD0328 led to a significant increase in cortical dopamine release in awake rodents and improved both conditi...
Facinicline is a partial agonist of the nicotinic alpha-7 (α7) receptor. It is used for the oral treatment of Alzheimer's. It was being co-developed by Roche an...
Highly selective α7 nAChR agonist (Ki = 26 nM) displaying negligible blockade of α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM). Found to be inactive against a panel of ...
Nelonicline is an Alpha7 nicotinic acetylcholine receptor(nAChR) agonist and Nicotinic acetylcholine receptor agonist. It plays a key role in inflammatory proce...
Cisatracurium besylate is a neuromuscular blocking agent that is used in liver transplant patient with safety. Cisatracurium besylate is also an enantiomer of A...
Varenicline (trade name Chantix in the USA and Champix in Canada, Europe and other countries, marketed by Pfizer, usually in the form of varenicline tartrate), ...
A neuronal nicotinic receptor agonist, showing high selectivity for the α4β2 subtype (Ki values are 26 and 36000 nM for α4β2 and α7 receptors respectively). Act...
PNU-120596 is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM.
EVP-6124 is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs). It shows selectivity for α7 nAChRs and did not activate or inhibi...
Catharanthine inhibits nicotinic receptor mediated diaphragm contractions with IC50 of 59.6 μM.
CP-601932 is a CNS-penetrant, high affinity, and selective α(4) β(2) nicotinic acetylcholine receptors partial agonist.
Encenicline, HCl salt
EVP-6124, its alpha-7 nicotinic acetylcholine receptor agonist, possesses a novel mechanism not previously seen in the scientific community: it acts as a co-ago...
ABT-594, also called as Tebanicline, the (R)-enantiomer of A-98593, is a potent synthetic non-opioid nicotinic analgesic drug. ABT-594 is a novel nAChR ligan wh...
CP-601927 is a CNS-penetrant, high affinity, and selective nicotinic acetylcholine receptor (nAChR) agonist.
Bradanicline acts as a partial agonist at the α7 subtype of the neural nicotinic acetylcholine receptors. It showed cognitive enhancing effects in animal studie...
A-366833 is a an agonist at neural nicotinic acetylcholine receptors selective for the α4β2 subtype.
Adiphenine HCl is a nicotinic receptor inhibitor with IC50 of 15 μM, used as an antispasmodic drug.
S16961 is a nicotinic receptor agonist with antihyperlipidaemic property which was developed for the treatment of Hyperlipidaemia in France (PO).
CP-810123 is a novel alpha 7 nAChR agonist with potential treatment for cognitive deficits associated with psychiatric or neurological conditions including schi...
Pancuronium results in open channel block of embryonic-type nicotinic acetylcholine receptor channels after coapplication of blocker and acetylcholine。