|Description||Adarotene is an atypical retinoid and a promising anti-tumour agent with selective apoptotic activity on the leukaemic blast. The anti-tumour activity of the compound has been associated with its capacity to induce DNA double stranded breaks.|
|Appearance||White to off-white solid|
|Synonyms||ST1926; ST 1926; ST-1926.|
Apoptosis Activator 2
Episilvestrol is a derivative of Silvestrol, which is a member of flavagline family of natural products from the genus of Aglaia,
A regulator of CXCR4 expression
Honokiol is the active principle of magnolia extract that inhibits Akt-phosphorylation and promotes ERK1/2 phosphorylation.
SMIP004 a novel inducer of cancer-cell selective apoptosis of human prostate cancer cells, at low micromolar concentration it upregulated p27 in various prostat...
Protopanaxdiol, an aglycon metabolic derivative of the protopanaxadiol-type ginseng saponin extracted from the roots of Panax ginseng C. A. Mey. It is apoptosis...
Epibrassinolide is a biologically active compound of the brassinosteroids that can be isolated from various plants. It belongs steroid-derived plant growth regu...
Desacetylcinobufotalin is apoptosis inducer. shows the inhibition effect to HepG2 cells (IC50 =0.0279μmol/ml) .
Adarotene is an atypical retinoid and a promising anti-tumour agent with selective apoptotic activity on the leukaemic blast. The anti-tumour activity of the co...
Silvestrol aglycone, extracted from Aglaia foveolata, could induce apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of e...
A member of flavagline family of natural products from the genus of Aglaia, induces apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway withou...
Elesclomol is a HSP-90 Inhibitor, and is a small-molecule bis(thio-hydrazide amide) with oxidative stress induction, pro-apoptotic, and potential antineoplastic...
Costunolide, a natural sesquiterpene compound with multiple biological activities; inhibits FPTase with IC50 of 20 μM, also inhibits telomerase with IC50 of 65-...
Ginsenoside Rg6, extracted from steamed notoginseng, exhibited significantly potent inhibitory effects on IL-12 p40 production in LPSstimulated BMDCs.
A natural compound, source from roots of Dioscorea opposita Thunb, could block the volt dependent form calcium channel in cellular membrane, and up-regulate the...
Perillyl Alcohol, or POH, a monoterpene derived from the mevalonate pathway in plants, induces apoptosis in colon tumor cells.
betulinic acid is a pentacyclic lupane-type triterpene derivative of betulin with antiinflammatory, anti-HIV and antineoplastic activities. Betulinic acid induc...
3,3’-Diindolylmethane is a derivative of a phytochemical natural compound found in Brassicaceae(Indole-3-carbinol).It is works as an activator of Chk2 that caus...