|Description||ADAMTS-5 (A Disintegrin And Metalloproteinase with ThromboSpondin motifs 5) is an aggrecanase-2. ADAMTS-5 is involved in the catabolism of aggrecan and collagen in the articular cartilage matrix during Osteoarthritis (OA).|
|Brife Description||ADAMTS-5 inhibitor|
TP 472 is a potent BRD9/7 inhibitor (Kd = 33 and 340 nM, respectively) with >30-fold selectivity for BRD9 over other bromodomains except BRD7.
N3PT inhibits transketolase activity in a cell based assay. Competitive inhibition of TK by N3PT in cells treated with increasing doses of thiamine, expressed a...
Ginsenoside C-K is an intestinal microbiota metabolite of ginsenoside Rb1, which possesses anti-proliferative and anti-inflammatory activities.
Eflornithine hydrochloride is a drug found to be effective in the treatment of facial hirsutism. It is a "suicide inhibitor," irreversibly binding to Ornithine ...
Bisoctrizole, a benzotriazole derivative, is a broad-spectrum ultraviolet radiation absorber, absorbing UVB as well as UVA ray. It could also reflect and scatte...
Motexafin Lutetium Hydrate
The hydrate form of Motexafin Lutetium that has been found to probably be effective in antineoplastic antiatheroscleroticand studies.
AP-24600 is a bio-active chemical, but no detailed information has been published yet.
FTI 276 trifluoroacetate salt
FTI 276 is a Ras CAAX peptidomimetic, a selective inhibitor of farnesyltransferase (FTase) with > 100-fold selectivity over geranylgeranyltransferase I (GGTase ...