ADAMTS-5 inhibitor - CAS 929634-33-3
Category: Inhibitor
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Molecular Formula:
C16H11ClF3N3OS3
Molecular Weight:
449.92
COA:
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Targets:
Others
Description:
ADAMTS-5 (A Disintegrin And Metalloproteinase with ThromboSpondin motifs 5) is an aggrecanase-2. ADAMTS-5 is involved in the catabolism of aggrecan and collagen in the articular cartilage matrix during Osteoarthritis (OA).
Brife Description:
ADAMTS-5 inhibitor
Purity:
99%
Synonyms:
5-[[5-[(4-chlorophenyl)methylsulfanyl]-1-methyl-3-(trifluoromethyl)pyrazol-4-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one
MSDS:
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InChIKey:
CVYPRDPBCXSVBN-UHFFFAOYSA-N
InChI:
InChI=1S/C16H11ClF3N3OS3/c1-23-14(26-7-8-2-4-9(17)5-3-8)10(12(22-23)16(18,19)20)6-11-13(24)21-15(25)27-11/h2-6H,7H2,1H3,(H,21,24,25)
Canonical SMILES:
CN1C(=C(C(=N1)C(F)(F)F)C=C2C(=O)NC(=S)S2)SCC3=CC=C(C=C3)Cl
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CAS 929634-33-3 ADAMTS-5 inhibitor

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