ACTB-1003 - CAS 939805-30-8
Catalog number:
939805-30-8
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C27H26F5N7O3
Molecular Weight:
591.53
COA:
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Targets:
FGFR
Description:
ACTB-1003 is an oral kinase inhibitor with multiple modes of action, targeting cancer mutations via FGFR inhibition FGFR1, angiogenesis through inhibition of VEGFR2, Tie-2, and induces apoptosis likely by targeting RSK and p70S6K. It is highly active with dose-dependent tumor growth inhibition in cell lines with FGFR genetic alterations - OPM2 human multiple myeloma and the murine leukemia Ba/F3-TEL-FGFR1.
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Purity:
>98%
MSDS:
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CAS 939805-30-8 ACTB-1003

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