ACT-281959 - CAS 1159501-31-1
Catalog number:
1159501-31-1
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C38H55N6O14P
Molecular Weight:
850.86
COA:
Inquire
Targets:
Others
Description:
This molecular is a prodrug of ACT-246475 which is a selective P2Y12 receptor antagonist with a wider therapeutic window in the rat model. ACT-281959 is the phosphate of ACT-246475 and showed antithrombotic efficacy after oral administration in the rat ferric chloride model. In May 2016, Phase-I development is ongoing in France.
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Purity:
98%
Appearance:
Powder
Synonyms:
butyl 4-((R)-3-(bis(((isopropoxycarbonyl)oxy)methoxy)phosphoryl)-2-(6-((S)-3-methoxypyrrolidin-1-yl)-2-phenylpyrimidine-4-carboxamido)propanoyl)piperazine-1-carboxylate
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
Cardiovascular disorders;antithrombotic
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
Canonical SMILES:
O=C(N1CCN(C([C@@H](NC(C2=NC(C3=CC=CC=C3)=NC(N4CC[C@@H](C4)OC)=C2)=O)CP(OCOC(OC(C)C)=O)(OCOC(OC(C)C)=O)=O)=O)CC1)OCCCC
Current Developer:
Originator:Actelion Pharmaceuticals
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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