ACT-246475 - CAS 1159500-34-1
Catalog number: 1159500-34-1
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C28H39N6O8P
Molecular Weight:
618.62
COA:
Inquire
Targets:
Others
Description:
This active molecular is a reversible and selective platelet P2Y12 receptor antagonist. IC50 value of ACT-246475 is 8.0 nM. ACT-246475 dose-dependently blocked thrombus formation in the rat ferric chloride model and displayed a wide therapeutic window. In May 2016, Phase-I development is ongoing in France.
Purity:
98%
Appearance:
Powder
Synonyms:
((R)-3-(4-(butoxycarbonyl)piperazin-1-yl)-2-(6-((S)-3-methoxypyrrolidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-3-oxopropyl)phosphonic acid
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
Cardiovascular disorders
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
Canonical SMILES:
O=C(N1CCN(C([C@@H](NC(C2=NC(C3=CC=CC=C3)=NC(N4CC[C@@H](C4)OC)=C2)=O)CP(O)(O)=O)=O)CC1)OCCCC
Current Developer:
Originator:Actelion Pharmaceuticals
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