|Description||Acetylcysteine is used mainly as a mucolytic, protects against acetaminophen overdose-induced hepatotoxicity by maintaining or restoring hepatic concentrations of glutathione.|
|Synonyms||SME-3110, MK-264, DU-23000|
Miglustat hydrochloride is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1).
NSC 146109 hydrochloride
NSC 146109 hydrochloride is a genotype-selective antitumor agent. It can activate p53-dependent transcription.
The sodium salt form of Disufenton, a benzenesulfonate compound, has been found to be a free radical scavenger that was once studied in acute ischaemic stroke t...
17-PA is an antagonist of neurosteroid GABA potentiation. It can selectively reduce the effects of 5α-reduced steroids compared to 5β-reduced steroids.
UNC 2327 is an allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3) (IC50 = 230 nM).
WWL 113 is a carboxylesterase Ces3 and Ces1f inhibitor (IC50 = ~100 nM) with minimal activity against a panel of other serine hydrolases. WWL 113 was indicated ...
JNJ-10329670 represents a novel class of immunosuppressive compounds with a highly potent (Ki ~30 nM)
Bitoscanate is an organic chemical compound used in the treatment of hookworms.
FQI 1 is a cell-permeable and reversible inhibitor of α-globin transcription factor CP2 (LSF; IC50 = 2.1 μM) and an antiproliferative. FQI 1 induces apoptosis i...
Aucubin is an iridoid glycoside with a wide range of biological activities, including anti-inflammatory, anti-microbial, anti-algesic as well as anti-tumor acti...
Warfarin is an anticoagulant applicated in the prevention of thrombosis and thromboembolism, the formation of blood clots in the blood vessels and their migrati...
Apocynin, also known as acetovanillone, is a natural organic compound structurally related to vanillin. It has been isolated from a variety of plant sources and...
L-Arginine is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis. It is an α-amino acid...
Equilin is one of the estrogens present in the mixture of estrogens isolated from horse urine and marketed as Premarin.
NVS-PAK1-1 is potent and specific allosteric PAK1 inhibitor (IC50= 5 nM) with selective over PAK2 and a panel of 442 kinases.
PF 4693627 is a potent, selective and orally bioavailable inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) that has the potential to treat inflamma...
N3PT inhibits transketolase activity in a cell based assay. Competitive inhibition of TK by N3PT in cells treated with increasing doses of thiamine, expressed a...
(Z)-MDL 105519 is the inactive isoform of MDL 105519 which is a high affinity NMDA glutamate receptor antagonist at the glycine site.
Rosmarinic acid is a naturally occurring hydroxylated compound occured in many plants. Rosmarinic acid exhibits agonist activity at GPR35 and shows antiviral, a...
6-Acetamidohexanoic acid is used in inhibiting the Gastrointestinal disease like gastric ulcer or small bowel inflammation. It is often used after some oral adm...